| Shakespeare character who says "I hate the Moor" | 58 |
| Shakespeare character who declares “Honesty’s a fool” | 65 |
| Shaker on the kids' show "Blue's Clues" | 57 |
| Shak. play whose original title was "Hey, You"? | 57 |
| Shak. play about a king who needs to loosen up once in a while? | 63 |
| Shak. play about a guy who has trouble meeting girls? | 53 |
| Shak. play about a fateful salad made by a famous French chef? | 62 |
| Shaffer play currently on Broadway starring Daniel Radcliffe | 60 |
| Shady Oscar winner for "Monster's Ball"? | 54 |
| Shades of it begin this puzzle's four longest answers | 57 |
| Sgt. Friday's request at the office supply store? | 53 |
| Sgt. Friday's comment at the office equipment store? | 56 |
| Seymour's love interest, once, on "The Simpsons" | 62 |
| Sex column that coined the word "santorum" | 52 |
| Sewing and scrapbooking, like, I don't know, I forget? | 58 |
| Seventeenth-century pope painted by Diego Velázquez | 54 |
| Seven-year-old TV character whose last name is Marquez | 54 |
| Seven-year period in which some get lucky for the first time | 60 |
| Seven-time Wimbledon champ of the 1980's and 90's | 57 |
| Seuss’s environmental spokesman, with “the” | 55 |
| Seuss character who "speaks for the trees" | 52 |
| Seuss book with environmental undertones, with "The" | 62 |
| Seuss book where the main character listens to noodle soup? | 59 |
| Settings for "Skyfall" and "Casino Royale" | 62 |
| Setting of Van Gogh's "Cafe Terrace at Night" | 59 |
| Setting of the sci-fi story "Out of the Silent Planet" | 64 |
| Setting of the painting "Washington Crossing the Delaware" | 68 |
| Setting of the opening scene of "Saving Private Ryan" | 63 |
| Setting of the oldest university in Spain (founded in 1218) | 59 |
| Setting of the Marlene Dietrich film "The Spoilers" | 61 |
| Setting of the first revolving restaurant in the U.S. | 53 |
| Setting of the climactic chase in "The Third Man" | 59 |
| Setting of the annual National Cowboy Poetry Gathering | 54 |
| Setting of the 2007 animated film "Persepolis" | 56 |
| Setting of Steinbeck's "The Pearl," familiarly | 60 |
| Setting of Mozart's only clarinet concerto: Abbr. | 53 |
| Setting of Mailer's "Ancient Evenings" | 52 |
| Setting of Joseph Conrad's "Heart of Darkness" | 60 |
| Setting of Barbara Kingsolver's "The Poisonwood Bible" | 68 |
| Setting numbered in multiples of the square root of 2 | 53 |
| Setting in Haydn's ''The Creation'' | 55 |
| Setting in "Call of Duty: Black Ops," informally | 58 |
| Setting for Verdi's "Simon Boccanegra" | 52 |
| Setting for Verdi's ''Simon Boccanegra'' | 60 |
| Setting for van Gogh's "The Yellow House" | 55 |
| Setting for van Gogh's "The Night Café" | 56 |
| Setting for van Gogh's "Cafe Terrace at Night" | 60 |
| Setting for Umberto Eco's "The Name of the Rose" | 62 |
| Setting for Tom Wolfe's "A Man in Full" | 53 |
| Setting for the 2001 film "No Man's Land" | 55 |
| Setting for the 1996 documentary "When We Were Kings" | 63 |
| Setting for some events in the 2006 and 1992 Olympics | 53 |
| Setting for Robert Frost's "A Masque of Mercy" | 60 |
| Setting for Radiohead's "Karma Police" video | 58 |
| Setting for part of the documentary "Sicko" | 53 |
| Setting for part of Kerouac's "On the Road" | 57 |
| Setting for part of "You Don't Mess With the Zohan" | 65 |
| Setting for part of "King Henry VI, Part 2" | 53 |
| Setting for part of "A Tale of Two Cities" | 52 |
| Setting for much of "Inglourious Basterds" | 52 |
| Setting for Martin Scorsese's "Kundun" | 52 |
| Setting for many episodes of TV's "Gilmore Girls" | 63 |
| Setting for Longfellow's "The Wreck of the Hesperus" | 66 |
| Setting for Henry James's "The American" | 54 |
| Setting for Edward Hopper's "Nighthawks" | 54 |
| Setting for Don DeLillo's "Underworld" | 52 |
| Setting for David's "The Death of Marat" | 54 |
| Setting for Clint Eastwood's "Flags of Our Fathers" | 65 |
| Setting for Charlie Chaplin's "The Gold Rush" | 59 |
| Setting for Cervantes's "El Gallardo Español" | 62 |
| Setting for C. S. Lewis's "The Last Battle" | 57 |
| Setting for a famous "Les Misérables" scene | 56 |
| Setting for "The Unbearable Lightness of Being" | 57 |
| Setting for "One Day in the Life of Ivan Denisovich" | 62 |
| Setting for "Miss Saigon" or "Platoon" | 58 |
| Setting for ''The Bridges of Madison County'' | 61 |
| Setting for ''Not Without My Daughter'' | 55 |
| Setting for ''Androcles and the Lion'' | 54 |
| Seth Rogen's role in "The 40-Year-Old Virgin" | 59 |
| Set of two contrary options that lead to the same unhappy conclusion | 68 |
| Set of software components packaged for release, briefly | 56 |
| Service station in a "Curb Your Enthusiasm" episode | 61 |
| Service found in the four longest Across answers herein | 55 |
| Server of Norm, Cliff and Frasier, on "Cheers" | 56 |
| Servant to Dr. Caius in "The Merry Wives of Windsor" | 62 |
| Sermon subject + a letter + trial subject + cat sound = ? | 57 |
| Serious faculty member when it comes to grading tests? | 54 |
| Series with a "Secrets of the Sun" episode | 52 |
| Series with "Duck Amuck" and "One Froggy Evening" | 69 |
| Series whose title character works for Mode magazine | 52 |
| Series that had 2007 crossover episodes with "CSI" | 60 |
| Series set at the Sterling Cooper Draper Pryce agency | 53 |
| Series set at the Princeton-Plainsboro Teaching Hospital | 56 |
| Series on the WB with the theme song "I'm a Survivor" | 67 |
| Serge Gainsbourg's "___ Petite Tasse d'Anxieté" | 68 |
| Sequoia in Calif. (world's largest living thing) | 52 |
| Sequence found in this puzzle's five longest answers | 56 |
| Sequel to the Sammy Davis Jr. film "Salt and Pepper" | 62 |
| Sentence fragments often beginning with "wh-" words | 61 |
| Senta's suitor in "The Flying Dutchman" | 53 |