| Highway of Northwest | 20 |
| Highway from Dawson Creek, B.C. | 31 |
| Highway covered in "The Milepost" | 43 |
| Former road to Fairbanks | 24 |
| Far North highway | 17 |
| Dawson Creek-to-Fairbanks highway | 33 |
| Alaska Highway, formerly | 24 |
| 1,523-mile highway | 18 |
| "Cross-country" highway built in 1942 | 47 |
| _____ Highway | 13 |
| ____ Highway | 12 |
| ___ Highway (WWII construction project) | 39 |
| ___ Highway (route through Whitehorse, Yukon) | 45 |
| ___ Highway (road through Ft. Nelson) | 37 |
| ___ Highway (old 1,500-mile route) | 34 |
| ___ Highway (historic route to Delta Junction) | 46 |
| "Untouchables" baddie | 31 |
| "Scarface" | 20 |
| Symbol of Prohibition era lawlessness | 37 |
| Alcatraz inmate of the 1930s | 28 |
| St. Valentine's Day Massacre organizer | 42 |
| Role for Robert De Niro | 23 |
| Notorious crime boss of Chicago | 31 |
| Noted 1931 indictee | 19 |
| Nemesis of Ness | 15 |
| Infamous booze boss in the 20's | 35 |
| Historical figure played by Robert De Niro | 42 |
| He flourished under Prohibition | 31 |
| Gangster a k a Scarface | 23 |
| Eliot Ness' foe | 19 |
| De Niro role | 12 |
| Chicago Outfit leader | 21 |
| 1967 role for Jason Robards | 27 |
| 1967 Jason Robards role | 23 |
| 1931 convictee | 14 |
| "Untouchables" target | 31 |
| "Boardwalk Empire" role | 33 |
| 'Scarface' | 18 |
| Cartoonist | 10 |
| Dogpatch creator | 16 |
| "Li'l Abner" cartoonist | 37 |
| Li'l Abner's creator | 28 |
| Fearless Fosdick's creator | 30 |
| Abner's creator | 19 |
| Yokums' creator | 19 |
| Dogpatch cartoonist | 19 |
| Creator of Dogpatch | 19 |
| Founder of Dogpatch | 19 |
| Dogpatch's creator | 22 |
| Daisy Mae's creator | 23 |
| 'Li'l Abner' creator | 32 |
| Mammy Yokum's creator | 25 |
| Creator of Stupefyin' Jones | 31 |
| Creator of Shmoos | 17 |
| Creator of Sadie Hawkins | 24 |
| Creator of Lena the Hyena | 25 |
| Creator of Fearless Fosdick | 27 |
| "Li'l Abner" creator | 34 |
| Shmoo creator | 13 |
| Lucifer Ornamental Yokum's creator | 38 |
| Jubilation T. Cornpone's creator | 36 |
| Creator of Marryin' Sam and Joe Btfsplk | 43 |
| Creator of Jubilation T. Cornpone | 33 |
| Creator of Earthquake McGoon | 28 |
| Cartoonist who helped start an amusement park in Arkansas | 57 |
| "L'il Abner" cartoonist | 37 |
| 'Li'l Abner' cartoonist | 35 |
| ''Li'l Abner'' cartoonist | 45 |
| The Rock | 8 |
| "The Rock" | 20 |
| San Francisco tourist attraction | 32 |
| San Francisco Bay tourist attraction | 36 |
| San Francisco Bay attraction | 28 |
| Rock of the Bay? | 16 |
| Pen called ''The Rock'' | 39 |
| Pelican, to Pedro | 17 |
| Much-filmed prison | 18 |
| Locale for 1996's ''The Rock'' | 50 |
| Island with a view of the Golden Gate | 37 |
| Infamous pen | 12 |
| Infamous island prison | 22 |
| Former penitentiary in San Francisco Bay | 40 |
| 1930s home for Capone | 21 |
| Medieval science | 16 |
| Transmutation | 13 |
| Subject studied by Isaac Newton | 31 |
| Skill in the online game World of Warcraft | 42 |
| Middle Ages pseudoscience | 25 |
| Method of transmutation | 23 |
| Medieval quest for gold | 23 |
| Medieval pseudoscience | 22 |
| Elementary science? | 19 |
| Big name in foil | 16 |
| Foil maker | 10 |
| Reynolds Wrap maker | 19 |
| Tennessee city | 14 |
| Big name in wrap | 16 |
| Aluminum manufacturer | 21 |
| Metal giant | 11 |
| Big name in siding | 18 |