| It's uncomfortable to be on it | 34 |
| It's uncertain when it's gray | 37 |
| It's unaccompanied in church | 32 |
| It's typically thrown eight feet | 36 |
| It's typically slow during rush hour | 40 |
| It's typically played indoors | 33 |
| It's typically made of leather or plush | 43 |
| It's typically easier to give than take | 43 |
| It's typically 72 for a course | 34 |
| It's typed with the left pinkie | 35 |
| It's two steps away from being a dollar sign | 48 |
| It's twisted during coercion | 32 |
| It's turned upside down when used | 37 |
| It's turned down for extra warmth | 37 |
| It's tuned to "My dog has fleas" | 46 |
| It's transfused in a transfusion | 36 |
| It's toward the back of the arena | 37 |
| It's tough to keep up with them | 35 |
| It's tough to find, but worth the effort | 44 |
| It's tough to fight, proverbially | 37 |
| It's tough to be in a lot of it | 35 |
| It's touched by three oceans | 32 |
| It's totally out of the mainstream | 38 |
| It's tossed at Spanish restaurants | 38 |
| It's tossed at some receptions | 34 |
| It's topped with Roquefort dressing | 39 |
| It's too important to ignore, literally | 43 |
| It's to the left of the Rive Droite | 39 |
| It's to the far right on freeways | 37 |
| It's tiny and sometimes attractive | 38 |
| It's tiny and it may get smashed | 36 |
| It's thrown at a bull's-eye | 35 |
| It's three levels below the major leagues | 45 |
| It's three days before Easter | 33 |
| It's the way things are going | 33 |
| It's the theme of this puzzle | 33 |
| It's the size of a small brain | 34 |
| It's the same for all customers | 35 |
| It's the root of all borscht | 32 |
| It's the right track, per Landon | 36 |
| It's the most likely to succeed | 35 |
| It's the hottest thing around | 33 |
| It's the geologist's fault | 34 |
| It's tested with Zener cards (abbr.) | 40 |
| It's tested with Zener cards | 32 |
| It's tested using the scientific method | 43 |
| It's terrifying if it won't open | 40 |
| It's ten spaces past "Go" | 39 |
| It's taken with delicate subjects | 37 |
| It's taken with a hand in the air | 37 |
| It's taken while wearing a cuff | 35 |
| It's taken into account in London | 37 |
| It's taken from twelve yards out | 36 |
| It's taken for trips in the desert | 38 |
| It's taken by some coll. seniors | 36 |
| It's taken after an order is given | 38 |
| It's synthesized in a three-step process | 44 |
| It's symbolized by yin and yang | 35 |
| It's symbolized by two wavy lines | 37 |
| It's symbolized by the color white | 38 |
| It's symbolized by the cedar | 32 |
| It's symbolized by caviar and Champagne | 43 |
| It's symbolized by a white flag | 35 |
| It's symbolized by a red circle on white | 44 |
| It's symbolized by a light bulb | 35 |
| It's swung in forests (Var.) | 32 |
| It's switched on a ten-speed | 32 |
| It's Swahili for "journey" | 40 |
| It's sure to give you problems | 34 |
| It's supposedly up a magician's sleeve | 46 |
| It's supposed to equal a mile | 33 |
| It's supposed to be circulated | 34 |
| It's supportive for those eating in bed | 43 |
| It's supported by a good shoe | 33 |
| It's support for art students | 33 |
| It's superior to Lake Superior: Abbr. | 41 |
| It's sunk at the end of the game | 36 |
| It's subject to modification | 32 |
| It's stuffed with green stuff | 33 |
| It's stuffed in a restaurant | 32 |
| It's stuffed in a high roller's pocket | 46 |
| It's stuck on Brooklyn theater floors | 41 |
| It's strummed in Maui, briefly | 34 |
| It's strapped around the head | 33 |
| It's stranded in the human body | 35 |
| It's stranded in police labs | 32 |
| It's straight from the horse's mouth | 44 |
| It's straight from the heart | 32 |
| It's stolen without being removed | 37 |
| It's stolen in an Austin Powers movie | 41 |
| It's stocked in an adult shop | 33 |
| It's still open to investigation | 36 |
| It's spread through spreadsheets | 36 |
| It's spotted in South America | 33 |
| It's spotted in Central America | 35 |
| It's spoken on Bering Island | 32 |
| It's spoken in los Estados Unidos | 37 |
| It's spoken in Berlin (Abbr.) | 33 |
| It's spent away from everyone else | 38 |
| It's southwest of Daytona Beach | 35 |