| Two Byrds and Eagleton | 22 |
| Two Byzantine emperors | 22 |
| Two caliphs | 11 |
| Two can sometimes take this | 27 |
| Two can take it, usually | 24 |
| Two can take this | 17 |
| Two can take this, sometimes | 28 |
| Two can't play at this game | 31 |
| Two caplets, e.g. | 17 |
| Two caplets, maybe | 18 |
| Two caplets, perhaps | 20 |
| Two caplets, say | 16 |
| Two capsules, maybe | 19 |
| Two capsules, perhaps | 21 |
| Two capsules, say | 17 |
| Two cars | 8 |
| Two cats owned by soldiers behind small earthen walls? | 54 |
| Two cents | 9 |
| Two cents worth | 15 |
| Two cents' worth | 20 |
| Two cents' worth, so to speak | 33 |
| Two cents, so they say | 22 |
| Two cents, so to speak | 22 |
| Two Chaneys | 11 |
| Two characters in "Lincoln"? | 38 |
| Two charts? | 11 |
| Two cherries on one stem? | 25 |
| Two chips, perhaps | 18 |
| Two cities in Italia | 20 |
| Two cities' story | 21 |
| Two cloned basketball centers play spectacularly? | 49 |
| Two close for comfort? | 22 |
| Two clubs | 9 |
| Two clubs, etc. | 15 |
| Two cold things | 15 |
| Two concerns for Cupid? | 23 |
| Two concerns of a secretive voodoo practicer? | 45 |
| TWO CONS | 8 |
| Two continents | 14 |
| Two continents as one | 21 |
| Two continents in one | 21 |
| Two courts | 10 |
| Two cowboy portrayers and an actor | 34 |
| Two cows in love but not married? | 33 |
| Two cross words | 15 |
| Two crosses to bear | 19 |
| Two cubed | 9 |
| Two culinary herbs | 18 |
| Two cups | 8 |
| Two cups full of milk? | 22 |
| Two cups that don't make a pint | 35 |
| Two cups, basically | 19 |
| Two cups? | 9 |
| Two dancers and a gourmet | 25 |
| Two days before St. Patrick's Day, e.g. | 43 |
| Two days in a Murphy movie | 26 |
| Two days in December | 20 |
| Two decades | 11 |
| Two decades after Cleopatra's death | 39 |
| Two December days | 17 |
| Two deficiencies? | 17 |
| Two desserts in one | 19 |
| Two diamonds and others | 23 |
| Two difficult alternatives | 26 |
| Two difficult choices | 21 |
| Two dimensional calculation | 27 |
| Two displays in the Sherlock Holmes Entomology Museum? | 54 |
| Two districts noted for restaurants | 35 |
| Two dogs? | 9 |
| Two dollars per pound, say | 26 |
| Two down from a queen | 21 |
| Two dozen sheets | 16 |
| Two drinks, for some | 20 |
| Two early saints | 16 |
| Two eighth notes, for iTunes, e.g. | 34 |
| Two English saints | 18 |
| Two eras or more | 16 |
| Two examples of silly talk | 26 |
| Two famous Goya paintings | 25 |
| Two famous Romans | 17 |
| Two fans? | 9 |
| Two favorite things for a dance-party-loving cassis producer? | 61 |
| Two features of a hurried golf game? | 36 |
| Two features of being tormented with endless replayings of "Dear God"? | 80 |
| Two features of interest on the sunken Titanic? | 47 |
| Two fifths of a dead man's hand | 35 |
| Two filming sessions for a skydiving scene? | 43 |
| Two fingers raised, e.g. | 24 |
| Two fins | 8 |
| Two fins' worth | 19 |
| Two fins, monetarily | 20 |
| TWO FIRE TRAILERS | 17 |
| Two five-spots | 14 |
| Two fivers | 10 |
| Two fives | 9 |
| Two fives for --- | 17 |
| Two fives for ___ | 17 |
| Two fives in Vegas | 18 |
| Two fives, for one | 18 |
| Two flowers going steady | 24 |