| Irritants | 9 |
| Irritants at a picnic | 21 |
| Irritants for the boss | 22 |
| Irritate | 8 |
| Irritate big-time | 17 |
| Irritate but good | 17 |
| Irritate by rubbing | 19 |
| Irritate greatly | 16 |
| Irritate psychologically | 24 |
| Irritate woolly mammals? | 24 |
| Irritate [solve the celeb puzzle series at avxwords.com] | 56 |
| Irritate, in a way | 18 |
| Irritate, like a skin-tight Spider-Man costume | 46 |
| Irritate: Colloq. | 17 |
| Irritate; fray | 14 |
| Irritated | 9 |
| Irritated by the littlest things | 32 |
| Irritated condition | 19 |
| Irritated Dubliner's complaint list? | 40 |
| Irritated interjection | 22 |
| Irritated moods | 15 |
| Irritated reactions | 19 |
| Irritated reply to 'Are you awake?' | 43 |
| Irritated state | 15 |
| Irritated states | 16 |
| Irritated with | 14 |
| Irritated, after "in" | 31 |
| Irritated, with "on" | 30 |
| Irritated, with "up" | 30 |
| Irritates | 9 |
| Irritates by rubbing | 20 |
| Irritates immensely | 19 |
| Irritates, as nerves | 20 |
| Irritates, like a masseuse? | 27 |
| Irritates, with "at" | 30 |
| Irritates, with "on" | 30 |
| Irritating | 10 |
| Irritating "Grey's Anatomy" nickname | 50 |
| Irritating aerosol | 18 |
| Irritating child | 16 |
| Irritating cry | 14 |
| Irritating desire | 17 |
| Irritating flier | 16 |
| Irritating insect | 17 |
| Irritating ninny | 16 |
| Irritating skin condition | 25 |
| Irritating skin sensation | 25 |
| Irritating snob | 15 |
| Irritating somebody | 19 |
| Irritating sort | 15 |
| Irritating sorts | 16 |
| Irritating sound | 16 |
| Irritating tingle | 17 |
| Irritating to the impatient | 27 |
| Irritating to the nose | 22 |
| Irritating vapor | 16 |
| Irritating vine | 15 |
| Irritating youngster | 20 |
| Irritatingly cheerful | 21 |
| Irritatingly high-pitched | 25 |
| Irritatingly proper person | 26 |
| Irritation | 10 |
| Irritation for a guy in a cast | 30 |
| Irritation for a web surfer | 27 |
| Irritation suffix | 17 |
| Irritation. | 11 |
| Irritations | 11 |
| Irritations for drivers | 23 |
| Irrritable | 10 |
| Irrupt | 6 |
| Irruptions | 10 |
| IRS worker | 11 |
| IRS "customers" | 25 |
| IRS abbr. | 9 |
| IRS activity | 12 |
| IRS agent | 9 |
| IRS agent's trial period? | 29 |
| IRS agent, casually | 19 |
| IRS agent, e.g. | 15 |
| IRS agents | 10 |
| IRS and IRA expert | 18 |
| IRS audit rep | 13 |
| IRS auditor's requests | 26 |
| IRS business designation | 24 |
| IRS calculator? | 15 |
| IRS challenger | 14 |
| IRS check | 9 |
| IRS check: Abbr. | 16 |
| IRS checks | 10 |
| IRS collections | 15 |
| IRS Commissioner (country singer) | 33 |
| IRS concern | 11 |
| IRS crackdown on two-seated carriages? | 38 |
| IRS data | 8 |
| IRS datum | 9 |
| IRS deadline month | 18 |
| IRS doings | 10 |
| IRS employee | 12 |
| IRS employee (Abbr.) | 20 |
| IRS employees | 13 |