| San Antonio landmark, with "the" | 42 |
| San Antonio mayor Julián, keynote speaker at the 2012 Democratic convention | 78 |
| San Antonio memorial | 20 |
| San Antonio mission | 19 |
| San Antonio NBA star Duncan | 27 |
| San Antonio player | 18 |
| San Antonio pro | 15 |
| San Antonio shrine | 18 |
| San Antonio shrine, with "the" | 40 |
| San Antonio siege site | 22 |
| San Antonio sight | 17 |
| San Antonio site | 16 |
| San Antonio site, with "the" | 38 |
| San Antonio Spur Ginóbili with three championship rings | 58 |
| San Antonio team | 16 |
| San Antonio team's current MVP? | 35 |
| San Antonio tourist attraction | 30 |
| San Antonio tourist destination | 31 |
| San Antonio tourist spot | 24 |
| San Antonio tourist stop | 24 |
| San Antonio's county | 24 |
| San Antonio-to-Amarillo dir. | 28 |
| San Antonio-to-Austin dir. | 26 |
| San Antonio-to-Corpus Christi dir. | 34 |
| San Antonio-to-Dallas dir. | 26 |
| San Antonio-to-Ft. Worth dir. | 29 |
| San Antonio-to-Laredo dir. | 26 |
| San Bernardino suburb | 21 |
| San Bernardino, vis-Ã -vis Los Angeles | 40 |
| San Clemente initials | 21 |
| San Diego air station whose pilots inspired "Top Gun" | 63 |
| San Diego area racetrack | 24 |
| San Diego athlete | 17 |
| San Diego attraction | 20 |
| San Diego ball club | 19 |
| San Diego ballplayer | 20 |
| San Diego band No ___ | 21 |
| San Diego baseballer | 20 |
| San Diego Chargers head coach Turner | 36 |
| San Diego Chicken's team | 28 |
| San Diego cleric | 16 |
| San Diego County beach town | 27 |
| San Diego County's San --- | 30 |
| San Diego court star | 20 |
| San Diego draw | 14 |
| San Diego footballer | 20 |
| San Diego has a renowned one | 28 |
| San Diego hitter | 16 |
| San Diego mascot's topper? | 30 |
| San Diego neighbor | 18 |
| San Diego nine | 14 |
| San Diego or San Francisco | 26 |
| San Diego Padres' stadium | 29 |
| San Diego player | 16 |
| San Diego pro | 13 |
| San Diego quarterback | 21 |
| San Diego section | 17 |
| San Diego setting: Abbr. | 24 |
| San Diego slugger | 17 |
| San Diego snacks | 16 |
| San Diego squad | 15 |
| San Diego State athlete | 23 |
| San Diego State athletes | 24 |
| San Diego State player | 22 |
| San Diego State team | 20 |
| San Diego State University athlete | 34 |
| San Diego steeds | 16 |
| San Diego suburb | 16 |
| San Diego suburb whose name means "the table" | 55 |
| San Diego Symphony conductor | 28 |
| San Diego team | 14 |
| San Diego team member | 21 |
| San Diego team upset? | 21 |
| San Diego time: Abbr. | 21 |
| San Diego tourist attraction | 28 |
| San Diego tourist magnet | 24 |
| San Diego treat | 15 |
| San Diego wives, perhaps | 24 |
| San Diego Zoo attraction | 24 |
| San Diego Zoo attraction? | 25 |
| San Diego Zoo attractions | 25 |
| San Diego Zoo inhabitant | 24 |
| San Diego __ | 12 |
| San Diego's area, for short | 31 |
| San Diego's Bai Yun and Gao Gao, e.g. | 41 |
| San Diego's founder Gaspar de ___ | 37 |
| San Diego's neighbor | 24 |
| San Diego's region, for short | 33 |
| San Diego's ___ Pines, site of the 2008 U.S. Open | 53 |
| San Diego-area horse-racing venue | 33 |
| San Diego-to-Albuquerque dir. | 29 |
| San Diego-to-Seattle rte. | 25 |
| San Diego-to-Tijuana dir. | 25 |
| San Diego-to-Vegas dir. | 23 |
| San Fernando creator of fake van Goghs? | 39 |
| San Fernando Valley city | 24 |
| San Fernando Valley community | 29 |
| San Fernando Valley district | 28 |
| San Fernando Valley locale | 26 |
| San Fernando Valley neighborhood | 32 |