| Sleep aid once advertised to "help you get your Z's" | 66 |
| Sledge who sang "When a Man Loves a Woman" | 52 |
| Sled dog with a statue in New York's Central Park | 53 |
| Slayer "Christ Illusion" single about vision? | 55 |
| Slave in Pearl S. Buck's "The Good Earth" | 55 |
| Slaughter whose "Mad Dash" won the 1946 World Series | 62 |
| Slaughter who dashed home to win the 1946 World Series | 54 |
| Slapping webbed feet, doing backflip into a stream, etc.? | 57 |
| Slangy suffix with "smack" or "sock" | 56 |
| Slangy subgenre for bands like X Japan, Dragon Ash and Luna Sea | 63 |
| Slangy ending for "smack" or "switch" | 57 |
| Slangy ending for ''yes'' or ''no'' | 67 |
| Slang term for a website's prominence on a popular search engine | 68 |
| Slang term derived from the sound of an edited-for-radio curse word | 67 |
| Skynyrd song about "outlaws, renegades, rebels" (Abbr.) | 65 |
| Skittles slogan ... or an alternate title for this puzzle | 57 |
| Skipper portrayer in "Gilligan's Island" | 54 |
| Skip, like the H's in "'enry 'iggins" | 59 |
| Skin care and cosmetics company that looks to be unrelated to Arthur | 68 |
| Skill not displayed by asking "Have you put on weight?" | 65 |
| Skiers seem to love it, especially early in the season | 54 |
| Skier Picabo finishing 11 places down from the bronze? | 54 |
| Skid Row "Slave to the Grind" power ballad | 52 |
| Skid Row "I'd stare a lifetime into your ___" | 59 |
| Sketched crudely, with "in" or "out" | 56 |
| Sketch show that hasn't had a black female regular since 2007 | 65 |
| Skater Oksana who was in "Blades of Glory" | 52 |
| Skater known as "America's sweetheart" | 52 |
| Skateboarding trick in which the feet don't leave the board | 63 |
| Skateboarding shoe brand named after an Egyptian god | 52 |
| Sixth-century year when the Kingdom of East Anglia was formed | 61 |
| Sixth-century year when the Armenian calendar begins | 52 |
| Sixth most abundant element in the Earth's crust | 52 |
| Sixth Greek letter, though it seems like it might be the last | 61 |
| Sixpence None the Richer covered them with "There She Goes" | 69 |
| Sixer legend whose number was also retired by the Nets, familiarly | 66 |
| Six-time Emmy nominee (and two-time winner) of the 1970s | 56 |
| Six-time All-Star third baseman of the 1970s Dodgers | 52 |
| Six-headed monster with twelve feet from the "Odyssey" | 64 |
| Six Flags Great Adventure roller coaster with a Spanish name | 60 |
| Six Flags coaster whose name is Spanish for "The Bull" | 64 |
| Situations where one person's gain is another's loss | 60 |
| Situation unlike the 2000 or 2004 presidential elections | 56 |
| Situation in which this puzzle's symptoms may appear | 56 |
| Situation at the start of a concert by singer Nicks? | 52 |
| Sitting through an entire GOP primary debate, for example | 57 |
| Site with the tagline "What are you doing?" | 53 |
| Site with an "I'm Feeling Lucky" button | 53 |
| Site whose slogan is "The front page of the internet" | 63 |
| Site that calls itself the front page of the internet | 53 |
| Site of Velázquez's "The Forge of Vulcan" | 58 |
| Site of the world's largest single reservoir of natural gas | 63 |
| Site of the World Trade Organization's headquarters | 55 |
| Site of the Woodrow Wilson Sch. of Public and Intl. Affairs | 59 |
| Site of the statue "Christ the Redeemer," familiarly | 62 |
| Site of the Otter River State Forest, gazetteer-style | 53 |
| Site of the largest WWII Allied Pacific amphibious assault | 58 |
| Site of the first Tomb Raider game's climactic finale | 57 |
| Site of the first nationally televised college basketball game | 62 |
| Site of the first British colony in the Caribbean, 1624 | 55 |
| Site of the 1974 fight known as "The Rumble in the Jungle" | 68 |
| Site of the 1973 Riggs/King "Battle of the Sexes" | 59 |
| Site of slippage ... both geographically and in this puzzle | 59 |
| Site of one of the world's most famous onion domes | 54 |
| Site of one of the Seven Wonders of the Ancient World | 53 |
| Site of Mt. Mitchell, highest U.S. point east of the Mississippi | 64 |
| Site of Jews' last stand against Romans: A.D. 72–73 | 62 |
| Site of four sold-out 1972 Elvis Presley concerts, for short | 60 |
| Site of Europe's Parkpop festival, with "The" | 59 |
| Site of a protest against the Afrikaans Medium Decree | 53 |
| Site of a memorable "When Harry Met Sally" scene | 58 |
| Site of a horrific 1993 ATF siege and also the Dr Pepper Museum | 63 |
| Site of a hit song's instrumental version, maybe | 52 |
| Site of a 2005 60th-anniversary memorial service, briefly | 57 |
| Site of a 1776 battle that gave New York City to the British | 60 |
| Site of "The Highest Marathon in the World" | 53 |
| Site near an outdoor recording session in "Help!" | 59 |
| Site mentioned in "The Ballad of Davy Crockett" | 57 |
| Site for singles with the tagline "Get Chosen" | 56 |
| Site for displaced homoerotic affection, at metal shows | 55 |
| Site depicted on California's America the Beautiful quarter | 63 |
| Site claiming to be "the front page of the Internet" | 62 |
| Sitcom with the theme song "I'm a Survivor" | 57 |
| Sitcom with the theme song "I'll Be There for You" | 64 |
| Sitcom with the catchphrase "Kiss my grits!" | 54 |
| Sitcom wife reprised by Gabrielle Union in a 2005 film | 54 |
| Sitcom whose titular character attended Copeland College | 56 |
| Sitcom where Shawn and Marlon work at a hair removal salon? | 59 |
| Sitcom title character who is called a "Virgin" | 57 |
| Sitcom that gives the backstory on getting to know a bug? | 57 |
| Sitcom star busted for pot in 1998 at his home in West Virginia | 63 |
| Sitcom spun off from "The Dukes of Hazzard" | 53 |
| Sitcom security device that often defeated its own purpose | 58 |
| Sitcom planet first mentioned in an episode of "Happy Days" | 69 |
| Sitcom originally titled "These Friends of Mine" | 58 |
| Sitcom most famous for "The Puppy Episode" | 52 |
| Sitcom in which the lead male actor magically changed in 1969 | 61 |
| Sitcom guy with a frequently upturned thumb, with "the" | 65 |
| Sitcom character who debuted in "Laura's First Date" | 66 |
| Sitcom about a family of Dresden residents raised by a single parent? | 69 |