| Sign of the maiden | 18 |
| Sign of the past | 16 |
| Sign of the ram | 15 |
| Sign of the sixties | 19 |
| Sign of the times | 17 |
| Sign of the times? | 18 |
| Sign of the twins | 17 |
| Sign of the zodiac | 18 |
| Sign of theatrical success | 26 |
| Sign of things not to come? | 27 |
| Sign of things to come | 22 |
| Sign of things to come? | 23 |
| Sign of things to go? | 21 |
| Sign of traffic impatience | 26 |
| Sign of treble? | 15 |
| Sign of triumph | 15 |
| Sign of tropical hospitality | 28 |
| Sign of trouble | 15 |
| Sign of trouble --> commercial writers | 41 |
| Sign of uncertainty | 19 |
| Sign of unfaithfulness | 22 |
| Sign of unhappiness | 19 |
| Sign of use | 11 |
| Sign of victory | 15 |
| Sign of virtue | 14 |
| Sign of volcanism | 17 |
| Sign of warm affection | 22 |
| Sign of warning | 15 |
| Sign of watchfulness | 20 |
| Sign of weeping | 15 |
| Sign of welcome | 15 |
| Sign of welcomeness | 19 |
| Sign of what's coming | 25 |
| Sign of what's to come | 26 |
| Sign of winter | 14 |
| Sign of winter? | 15 |
| Sign of worry | 13 |
| Sign of zodiac | 14 |
| Sign off | 8 |
| Sign off on | 11 |
| Sign off on, simply | 19 |
| Sign off on: Abbr. | 18 |
| Sign often seen on median strips | 32 |
| Sign on | 7 |
| Sign on a "puerta" | 28 |
| Sign on a B'way booth | 25 |
| Sign on a bargain | 17 |
| Sign on a basket | 16 |
| Sign on a bass's staff | 26 |
| Sign on a bathroom door | 23 |
| Sign on a British restroom door | 31 |
| Sign on a building, and the theme of this puzzle | 48 |
| Sign on a bus | 13 |
| Sign on a car on a lot | 22 |
| Sign on a cheap diner | 21 |
| Sign on a construction site fence | 33 |
| Sign on a diner | 15 |
| Sign on a divided highway | 25 |
| Sign on a door | 14 |
| Sign on a fence | 15 |
| Sign on a fence, perhaps | 24 |
| Sign on a five-and-ten counter | 30 |
| Sign on a fortune teller's door? | 36 |
| Sign on a galley | 16 |
| Sign on a gate | 14 |
| Sign on a giveaway | 18 |
| Sign on a Goodyear store? | 25 |
| Sign on a grade school door | 27 |
| Sign on a hacker's door? | 28 |
| Sign on a highway | 17 |
| Sign on a hotel-room door | 25 |
| Sign on a locked door | 21 |
| Sign on a locked lavatory | 25 |
| Sign on a moping teen's door | 32 |
| Sign on a mountain road | 23 |
| Sign on a movie marquee | 23 |
| Sign on a music store door? | 27 |
| Sign on a new lawn | 18 |
| Sign on a painting, sometimes | 29 |
| Sign on a plane facility | 24 |
| Sign on a rental unit | 21 |
| Sign on a road that leads to a shoe company? | 44 |
| Sign on a saloon door | 21 |
| Sign on a school door | 21 |
| Sign on a second | 16 |
| Sign on a shop's door | 25 |
| Sign on a sidewalk food cart | 28 |
| Sign on a small hotel | 21 |
| Sign on a Spanish word | 22 |
| Sign on a St. Paul diner? | 25 |
| Sign on a staff | 15 |
| Sign on a store door | 20 |
| Sign on a store window | 22 |
| Sign on a store's door | 26 |
| Sign on a street | 16 |
| Sign on a switch | 16 |
| Sign on a table | 15 |
| Sign on a ticket booth | 22 |
| Sign on a travel agent's wall? | 34 |
| Sign on a tray of samples | 25 |