| Sent a duplicate letter to, briefly | 35 |
| Sent a "Dear John" letter, say | 40 |
| Sensitive to other's feelings | 33 |
| Sensitive piece of personal data, sometimes | 43 |
| Sensitive information is often shared on it | 43 |
| Sensitive and melodramatic, in slang | 36 |
| Sensible, Ã la George Bush Sr. | 33 |
| Sensible, and alternate title of this puzzle | 44 |
| Senses Fail "___ on This" | 35 |
| Senses Fail "Buried ___" | 34 |
| Sensei's place in the Pennsylvania mountains? | 49 |
| Sense sorely lacking in some people | 35 |
| Sense of tedium, with "the" | 37 |
| Sense of psychological completeness | 35 |
| Sense of humor, it's been said | 34 |
| Sense of house-selling skills nearby? | 37 |
| Sense and Sensibility philanderer | 36 |
| Sensational 1990s-2000s talk show host | 38 |
| Sensation in a loop-the-loop, e.g. | 34 |
| Sensation experienced during mastication | 40 |
| Seniors' nest eggs, for short | 33 |
| Seniors often have trouble with it | 34 |
| Senior-most Justice of the Supreme Court | 40 |
| Senior's nest egg, for short | 32 |
| Senior members of diplomatic corps | 34 |
| Senior citizens, with "the" | 37 |
| Senior citizen's aide (abbr.) | 33 |
| Senior airman's superior: Abbr. | 35 |
| Seneca's prediction in "Medea" | 44 |
| Seneca's "reasoning animal" | 41 |
| Seneca the Younger's student | 32 |
| Sends to the White House, perhaps | 33 |
| Sends millions of unwanted messages, say | 40 |
| Sends mass mailings to, in a way | 32 |
| Sends back, as to await a hearing | 33 |
| Sends a written message to by cell phone | 40 |
| Sendoff for a Christmas shopper? | 32 |
| Sending to the canvas, in boxing | 32 |
| Sending out a radar-jamming signal? | 35 |
| Sending Gossage to an early shower? | 35 |
| Sending flowers to a courtroom worker? | 38 |
| Sending a ___ the moon (1960's goal) | 40 |
| Sender of news messages, once (3-7) | 35 |
| Sender of many monthly checks (abbr.) | 37 |
| Sender of care packages to soldiers | 35 |
| Sender of an anonymous valentine, perhaps | 41 |
| Sendak’s “Where the Wild Things ___” | 48 |
| Send, as a note to a kindergarten teacher | 41 |
| Send, "Star Trek"-style | 33 |
| Send to one's room without supper, say | 42 |
| Send tax returns via the Internet | 33 |
| Send something down the wrong pipe, as it were | 46 |
| Send Rover over for the weekend? | 32 |
| Send playwright Terrence back into custody? | 43 |
| Send out, in the realm of physical media | 40 |
| Send out a save the date card, e.g. | 35 |
| Send more supplies to the troops | 32 |
| Send in one's tax forms without using a stamp | 49 |
| Send for a special bridal accessory? | 36 |
| Send for a different size, perhaps | 34 |
| Send flowers and love letters, say | 34 |
| Send explicit come-ons by cell phone | 36 |
| Send elsewhere, as to a specialist | 34 |
| Send a telegraph to designer Pierre? | 36 |
| Send a tax return via cyberspace | 32 |
| Send a message in Morse code, e.g. | 34 |
| Send a kid from Santiago to Alaska? | 35 |
| Send a document over phone lines | 32 |
| Send a center to Sacramento, say | 32 |
| Senatus Populusque Romanus: Abbr. | 33 |
| Senators' advantage in Ottawa | 33 |
| Senators hear it before facing off | 34 |
| Senators Bunning, DeMint, Risch, and Webb | 41 |
| Senators and representatives, for short | 39 |
| Senator/campaigner Joe from Delaware | 36 |
| Senator's adjective for a colleague | 39 |
| Senator who succeeded John Stennis | 34 |
| Senator who served on the USS Gridley | 37 |
| Senator who isn't a strict schoolteacher | 44 |
| Senator who gave Golden Fleece awards | 37 |
| Senator Thurmond who left office at age 100 | 43 |
| Senator that gave his name to a federal aid grant | 49 |
| Senator Scott from South Carolina | 33 |
| Senator Schumer's predecessor | 33 |
| Senator Sanders of Vt., on ballots | 34 |
| Senator Sam who investigated Watergate | 38 |
| Senator Sam of the Watergate hearings | 37 |
| Senator Phil who co-authored a budget act | 41 |
| Senator or congressman, for short | 33 |
| Senator Jon of non-factual statements | 37 |
| Senator Jake who flew on space shuttle Discovery | 48 |
| Senator from Kansas or North Carolina | 37 |
| Senator from California from 1969 to 1993 | 41 |
| Senator formerly on "SNL" | 35 |
| Senator for whom an IRA is named | 32 |
| Senator for 47 straight years, a Senate record | 46 |
| Senator Feinstein of California | 32 |
| Senator Christopher from Connecticut | 36 |
| Senator Alexander from Tennessee | 32 |
| Senator aboard "Discovery" | 36 |