| Seuss villain with a heart two sizes too small | 46 |
| Seuss title character and namesakes | 35 |
| Seuss story concerned with Truffula trees | 41 |
| Seuss classic narrated by Morris McGurk | 39 |
| Seuss character, with "The" | 37 |
| Seuss book arguing in favor of libertarianism? | 46 |
| Seuss book about surpassing actress Winger? | 43 |
| Seuss book about destroying a marijuana farm? | 45 |
| Seuss book about destroying a kitchen item? | 43 |
| Seuss book about a musical breakfast? | 37 |
| Seurat's "___ Baignade" | 37 |
| Settles through an angry confrontation | 38 |
| Settles on, with "for" | 32 |
| Settles down for the night, in the forest | 41 |
| Settles a debt (with "up") | 36 |
| Settler in the Canadian Maritimes | 33 |
| Settler after a conquest of 1066 | 32 |
| Settlement negotiated by one's ancestors? | 45 |
| Settlement established in 1624 by the Dutch | 43 |
| Settlement established by the Dutch | 35 |
| Settled in for the night, with "down" | 47 |
| Settled down on a branch, as a bird | 35 |
| Settled an account (with "up") | 40 |
| Settled a disagreement, in a way | 32 |
| Settle one debt by incurring another | 36 |
| Settle on (with "for") | 32 |
| Settle comfortably, as into a chair | 35 |
| Settle a lover's spat nicely | 32 |
| Settings of Delacroix and Ingres paintings | 42 |
| Settings for some victory dances | 32 |
| Settings for some TV dramas: Abbr. | 34 |
| Settings for some TV dramas (abbr.) | 35 |
| Settings for some special deliveries: Abbr. | 43 |
| Settings for some hospital dramas (abbr.) | 41 |
| Settings for much stitching, briefly | 36 |
| Settings for "Junkyard Wars" | 38 |
| Setting where a medium isn't rare | 37 |
| Setting up production factories, e.g. | 37 |
| Setting that makes things right? | 32 |
| Setting that affects depth of field | 35 |
| Setting on the Mississippi: Abbr. | 33 |
| Setting of William the Conqueror's castle | 45 |
| Setting of Volcanoes National Park | 34 |
| Setting of Van Gogh's "Bedroom" | 45 |
| Setting of two Shakespeare plays | 32 |
| Setting of the world's largest book fair | 44 |
| Setting of the World Chess Hall of Fame: Abbr. | 46 |
| Setting of the University of Jordan | 35 |
| Setting of the Royal Botanic Gardens | 36 |
| Setting of the Pro Football Hall of Fame | 40 |
| Setting of the Peabody Museum of Natural History | 48 |
| Setting of the NYC restaurant Balthazar | 39 |
| Setting of the Norwegian Nobel Institute | 40 |
| Setting of the Nobel Peace Center | 33 |
| Setting of the New York Giants' training camp | 49 |
| Setting of the mountain Puu Kukui | 33 |
| Setting of the House of the Seven Gables | 40 |
| Setting of the FX series "Over There" | 47 |
| Setting of the former Phillips U. | 33 |
| Setting of the Dasht-i-Lut desert | 33 |
| Setting of the Chisholm Trail Expo Center | 41 |
| Setting of the Charge of the Light Brigade | 42 |
| Setting of the castle Rocca Maggiore | 36 |
| Setting of the board game Diplomacy | 35 |
| Setting of the Big 12's Jack Trice Stadium | 46 |
| Setting of the Argonaut Conference | 34 |
| Setting of the 2012 film "John Carter" | 48 |
| Setting of the 2010 film "Leap Year" | 46 |
| Setting of the 1945 Pulitzer Prize photo | 40 |
| Setting of St. Columba's missionary work | 44 |
| Setting of Raymond James Stadium | 32 |
| Setting of Queen Beatrix International Airport | 46 |
| Setting of Queen Beatrix Airport | 32 |
| Setting of Munch's "Scream" | 41 |
| Setting of Middle East Technical University | 43 |
| Setting of Mexico's Pyramid of the Sun | 42 |
| Setting of Maugham's "Rain" | 41 |
| Setting of Margaret Mead's first book | 41 |
| Setting of many Washington Irving tales | 39 |
| Setting of many Stephen King novels | 35 |
| Setting of many New Yorker cartoons | 35 |
| Setting of many Mario Vargas Llosa novels | 41 |
| Setting of many a teen movie scene | 34 |
| Setting of many a Stephen King novel | 36 |
| Setting of many a murder mystery | 32 |
| Setting of many a Monet painting | 32 |
| Setting of many "Friends" scenes | 42 |
| Setting of Kubla Khan's palace | 34 |
| Setting of Johnny Depp's feature film debut | 47 |
| Setting of Hopper's "Nighthawks" | 46 |
| Setting of Hitchcock's "Notorious" | 48 |
| Setting of HBO's "Big Love" | 41 |
| Setting of Camus's "The Stranger" | 47 |
| Setting of Camus's "The Plague" | 45 |
| Setting of Camus's "The Fall" | 43 |
| Setting of Camus' "The Plague" | 44 |
| Setting of an Innoventions exhibit | 34 |
| Setting of an iconic WWII photograph | 36 |
| Setting of a sci-fi slave story? | 32 |
| Setting of a Boston-N.Y. rivalry | 32 |