| Octopus's locale | 20 |
| Octopus's relative | 22 |
| Octopus, e.g. | 13 |
| Octopuses have many | 19 |
| Octopuslike | 11 |
| Octoroon | 8 |
| Octubre is part of it | 21 |
| Octubre o noviembre | 19 |
| Octubre, por ejemplo | 20 |
| Ocular | 6 |
| Ocular affliction for an iced dessert lover? | 44 |
| Ocular ailment | 14 |
| Ocular annoyance | 16 |
| Ocular circle | 13 |
| Ocular cleaning aids | 20 |
| Ocular cleansing cup | 20 |
| Ocular cleansing receptacle | 27 |
| Ocular concern | 14 |
| Ocular distress | 15 |
| Ocular flare-up | 15 |
| Ocular fluid or wet wit? | 24 |
| Ocular infection | 16 |
| Ocular inflammation | 19 |
| Ocular inflammation also known as conjunctivitis | 48 |
| Ocular irritants | 16 |
| Ocular irritation | 17 |
| Ocular irritations | 18 |
| Ocular malady | 13 |
| Ocular nuisance | 15 |
| Ocular parts | 12 |
| Ocular pest | 11 |
| Ocular prefix | 13 |
| Ocular problem | 14 |
| Ocular problems | 15 |
| Ocular protection | 17 |
| Ocular ring | 11 |
| Ocular rinsing aids | 19 |
| Ocular signs of planning? | 25 |
| Ocular socket | 13 |
| Ocular sphincter | 16 |
| Ocular washing aid | 18 |
| Ocular woe | 10 |
| Ocular woes | 11 |
| Oculist's interest | 22 |
| Oculist's item | 18 |
| Oculist's piece | 19 |
| Oculist's specialty | 23 |
| Oculist's study | 19 |
| Oculus mundi | 12 |
| OD respondent | 13 |
| Oda | 3 |
| Oda or refectory | 16 |
| Oda site | 8 |
| Oda ___ Brown (Oscar-winning role) | 34 |
| Oda ___ Brown, Whoopi in "Ghost" | 42 |
| Oda _____ (Whoopi's role in "Ghost") | 50 |
| Odalisque's abode | 21 |
| Odalisque's home | 20 |
| Odalisque's place | 21 |
| Odalisque's quarters | 24 |
| Odalisque's residence | 25 |
| Odalisques serve them | 21 |
| Odalisques' abode | 21 |
| Odalisques' places | 22 |
| Odalisques, e.g. | 16 |
| Odd | 3 |
| Odd and even, at times | 22 |
| Odd and funny | 13 |
| Odd article to wear with a turtleneck | 37 |
| Odd attire for “casual Friday” | 38 |
| Odd behaviors | 13 |
| Odd cat | 7 |
| Odd chap | 8 |
| Odd character | 13 |
| Odd character on your lawn | 26 |
| Odd circus performer | 20 |
| Odd collection | 14 |
| Odd container for baby back ribs? | 33 |
| Odd container for cattle herders? | 33 |
| Odd container for charitable gifts? | 35 |
| Odd container for collector's sample coin? | 46 |
| Odd container for troubles? | 27 |
| Odd container for what's all in your head? | 46 |
| Odd counterpart? | 16 |
| Odd couple | 10 |
| Odd couple or dead ends? | 24 |
| Odd couple? | 11 |
| Odd double container for gift fruit? | 36 |
| Odd duck | 8 |
| Odd ending? | 11 |
| Odd feeling | 11 |
| Odd fellow | 10 |
| Odd fellows | 11 |
| Odd Fellows' meeting place | 30 |
| Odd flea market | 15 |
| Odd from a conventional viewpoint | 33 |
| Odd Future member Frank who recently came out | 45 |
| Odd Future release, e.g. | 24 |
| Odd group that included Jackie | 30 |
| Odd group that included Sammy Davis, Jr. | 40 |