| Middle-earth creator | 20 |
| Middle-earth beings | 19 |
| Middle-earth beast | 18 |
| Middle-earth baddie | 19 |
| Middle-ear membrane | 19 |
| Middle-ear bone | 15 |
| Middle-distance runner Sebastian | 32 |
| Middle-distance runner | 22 |
| Middle-class conformist | 23 |
| Middle-class | 12 |
| Middle-age woe | 14 |
| Middle-age spread material | 26 |
| Middle-age spread | 17 |
| Middle-age problem | 18 |
| Middle-age concern | 18 |
| Middle-age bulge | 16 |
| Middle-age birthdays | 20 |
| Middle, to Kate Middleton | 25 |
| Middle, to Brits | 16 |
| Middle, to British | 18 |
| Middle, in law | 14 |
| Middle, in Italy | 16 |
| Middle's middle | 19 |
| Middle ___ (period from 500 to 1500 years ago) | 46 |
| Middle ___ | 10 |
| Middle __ | 9 |
| Middle year of Nero's reign | 31 |
| Middle X? | 9 |
| Middle X, say | 13 |
| Middle X, maybe | 15 |
| Middle X or O, perhaps | 22 |
| Middle X or O | 13 |
| Middle X of X-X-X | 17 |
| Middle x | 8 |
| Middle words on a quarter | 25 |
| Middle words of a famous palindrome | 35 |
| Middle word of Descartes' conclusion | 40 |
| Middle word in the motto of the French Revolution | 49 |
| Middle word in a Led Zeppelin title | 35 |
| Middle word in a court case | 27 |
| Middle West region | 18 |
| Middle weights? | 15 |
| Middle weight? | 14 |
| Middle weight | 13 |
| Middle voice | 12 |
| Middle traffic-light color | 26 |
| Middle third of a famous motto | 30 |
| Middle square, say | 18 |
| Middle square, maybe | 20 |
| Middle sister on "The Brady Bunch" | 44 |
| Middle Simpson | 14 |
| Middle section of "Hamlet" | 36 |
| Middle schooler, maybe | 22 |
| Middle school student, say | 26 |
| Middle school student's item | 32 |
| Middle school stage, commonly | 29 |
| Middle school pupils | 20 |
| Middle school outburst | 22 |
| Middle school marks? | 20 |
| Middle school liability | 23 |
| Middle school insult | 20 |
| Middle School in Montreal | 25 |
| Middle school grade | 19 |
| Middle school Girl Scout | 24 |
| Middle school entrant, e.g. | 27 |
| Middle school contraband | 24 |
| Middle sch. subj. | 17 |
| Middle Sch. | 11 |
| Middle sax? | 11 |
| Middle row | 10 |
| Middle range | 12 |
| Middle pts. | 11 |
| Middle pt. | 10 |
| Middle properties on the four sides of a Monopoly board: Abbr. | 62 |
| Middle points | 13 |
| Middle point | 12 |
| Middle piece of Tokyo? | 22 |
| Middle parts of Japan? | 22 |
| Middle part of many signatures: Abbr. | 37 |
| Middle part of many plays | 25 |
| Middle part of a Shakespearean play | 35 |
| Middle part of a Shakespeare play | 33 |
| Middle part of a pedestal | 25 |
| Middle part of a Men At Work song title | 39 |
| Middle part of a kids' game | 31 |
| Middle part of a Caesarean boast | 32 |
| Middle part | 11 |
| Middle or high follower | 23 |
| Middle of __ (the boondocks) | 28 |
| Middle of __ (remote place) | 27 |
| Middle of XXX or OOO | 20 |
| Middle of XXX | 13 |
| Middle of Venezuela? | 20 |
| Middle of two quotes | 20 |
| Middle of tongue twister | 24 |
| Middle of three in a row? | 25 |
| Middle of three in a row | 24 |
| Middle of three black keys | 26 |
| Middle of this century | 22 |
| Middle of the weak? | 19 |