| Popular video game series discontinued in 2011 | 46 |
| Popular video game of the late 1990s | 36 |
| Popular video game franchise since 2001 | 39 |
| Popular video game avatars | 26 |
| Popular video game | 18 |
| Popular vice | 12 |
| Popular Via of Rome | 19 |
| Popular version of a design principle acronym spelled out by the starts of this puzzle's four longest answers | 113 |
| Popular vehicle | 15 |
| Popular veh. | 12 |
| Popular van Gogh painting | 25 |
| Popular Valentine's Day items | 33 |
| Popular Valentine's Day gift | 32 |
| Popular vacation trip | 21 |
| Popular vacation spot, with "the" | 43 |
| Popular vacation spot | 21 |
| Popular vacation month | 22 |
| Popular vacation locales | 24 |
| Popular vacation locale | 23 |
| Popular vacation isle | 21 |
| Popular vacation island | 23 |
| Popular vacation destination | 28 |
| Popular urbanite | 16 |
| Popular uprising | 16 |
| Popular Upper East Side restaurant until 2011 | 45 |
| Popular Unix scripting language | 31 |
| Popular umbrella brand | 22 |
| Popular U.S. board game since 1959 | 34 |
| Popular U.K. mag | 16 |
| Popular typeface | 16 |
| Popular type option | 19 |
| Popular twosomes | 16 |
| Popular TV war sitcom | 21 |
| Popular TV star | 15 |
| Popular TV series | 17 |
| Popular TV school | 17 |
| Popular TV rerun | 16 |
| Popular TV program | 18 |
| Popular TV police drama | 23 |
| Popular TV personality (11/20/1932-6/2/2012) | 44 |
| Popular TV personality | 22 |
| Popular TV news magazine | 24 |
| Popular TV miniseries: 1977 | 27 |
| Popular TV drama set in Las Vegas | 33 |
| Popular TV drama of the '80s | 32 |
| Popular TV drama | 16 |
| Popular TV counselor | 20 |
| Popular TV comic, for short | 27 |
| Popular TV co-host | 18 |
| Popular TV chef | 15 |
| Popular Tuscan city | 19 |
| Popular tune players | 20 |
| Popular tune for tenor or accordion | 35 |
| Popular tune for a tenor | 24 |
| Popular tune around Halloween | 29 |
| Popular tune | 12 |
| Popular tub plant | 17 |
| Popular truck type | 18 |
| Popular tropical destination | 28 |
| Popular tribute | 15 |
| Popular trend | 13 |
| Popular tree type | 17 |
| Popular treat to split | 22 |
| Popular treat since 1912 | 24 |
| Popular transformation | 22 |
| Popular toys since 1961 | 23 |
| Popular toys | 12 |
| Popular Toyota models | 21 |
| Popular Toyota | 14 |
| Popular toy trucks, for short | 29 |
| Popular toy since 1964 | 22 |
| Popular toy company | 19 |
| Popular toy car collectible | 27 |
| Popular toy car | 15 |
| Popular tower? | 14 |
| Popular tower | 13 |
| Popular tourist spots | 21 |
| Popular tourist spot in western Wyoming | 39 |
| Popular tourist spot | 20 |
| Popular tourist destinations | 28 |
| Popular tourist destination of Southeast Asia | 45 |
| Popular tourist city | 20 |
| Popular tourist attractions | 27 |
| Popular tourist areas | 21 |
| Popular tour area | 17 |
| Popular topping | 15 |
| Popular topic with lyricists | 28 |
| Popular Tonka toys | 18 |
| Popular toaster waffles | 23 |
| Popular toast | 13 |
| Popular title article | 21 |
| Popular tire maker | 18 |
| Popular times for Tours tours | 29 |
| Popular throat soother | 22 |
| Popular thirst quencher | 23 |
| Popular thing, slangily | 23 |
| Popular thing, briefly | 22 |
| Popular thesaurus | 17 |
| Popular theater name | 20 |
| Popular Texas tourist site | 26 |