| St. Louis Stars outfielder in the Hall of Fame | 46 |
| St. Louis hockey team sold to a high school? | 44 |
| St. Louis Gateway Arch architect | 32 |
| St. Louis Cardinals nickname in 1934 | 36 |
| St. Louis Cardinals great Slaughter | 35 |
| St. Louis bridge named for its builder | 38 |
| St. Louis band that failed to shake it up? | 42 |
| St. Louis arch designer Saarinen | 32 |
| St. Louis Arch architect Saarinen | 33 |
| St. Lawrence Seaway port of entry | 33 |
| St. Lawrence Islands Natl. Park setting | 39 |
| St. Kitts and ___ (Caribbean nation) | 36 |
| St. Jude Children's Hospital founder | 40 |
| St. John's ___ (herbal remedy) | 34 |
| St. John's __: herbal remedy | 32 |
| St. John's athletes, until 1994 | 35 |
| St. John Telegraph Journal cartoonist | 37 |
| St. James' Piccadilly designer | 34 |
| St. in which most of Yellowstone is located | 43 |
| St. Gotthard Tunnel passes through one | 38 |
| St. Francis ___ (French prelate) | 32 |
| St. Edward's University site | 32 |
| St. consisting of two peninsulas | 32 |
| St. Bernard in New Orleans, e.g.: Abbr. | 39 |
| St. Basil's Cathedral locale | 32 |
| St. Basil's Cathedral feature | 33 |
| St. Bartholomew's Day massacre victim | 41 |
| St. Augustine's locale: Abbr. | 33 |
| St. Andrews golf club member, typically | 39 |
| St. Agnes's ___ (January 20) | 32 |
| St. Agnes's or St. John's | 33 |
| St. -- (one of the Virgin Islands) | 34 |
| St ______, New Brunswick Port of Call | 37 |
| St _____, Newfoundland port of call | 35 |
| St _____, Newfoundland's Capital | 37 |
| St ____ , Quebec Border Crossing | 32 |
| St ___ (PQ address, or poet Cohen) | 35 |
| St _____ , New Brunswick Border Crossing | 42 |
| Srs. still living in the dorm, say | 34 |
| Sri Lanka, to 18th-century Persians | 35 |
| Sra.'s neighboring counterpart | 34 |
| SrA's superior on the Air Force base | 40 |
| Squishy Hasbro toy used with a launcher | 39 |
| Squishee seller on "The Simpsons" | 43 |
| Squishee seller of "The Simpsons" | 43 |
| Squishee purveyor on "The Simpsons" | 45 |
| Squish, squash or squelch, in a way | 35 |
| Squirting flower or dribble glass | 33 |
| Squirrel's partner, to Boris and Natasha | 44 |
| Squirrel on "Dora the Explorer" | 41 |
| Squirrel Nut Zippers "Put a ___ on It" | 48 |
| Squirrel in the Maisy children's books | 42 |
| Squire whose last name means "paunch" | 47 |
| Squire in "The Faerie Queene" | 39 |
| Squire in "Silas Marner" | 34 |
| Squire carrying the armor of a knight | 37 |
| Squinting toon who's an alumnus of Rutgers | 46 |
| Squiggly mark in "señor" | 37 |
| Squiggly line in "piñata" | 38 |
| Squiggle in "señor" | 32 |
| Squiggle in "piñata" | 33 |
| Squidward's neighbor on Nickelodeon | 39 |
| Squid-like creatures in Super Mario Bros. | 41 |
| Squid in its own ink, empanadas, etc. | 37 |
| Squeezed (with "out"), but barely | 43 |
| Squeeze the water out of Southern greens? | 41 |
| Squeeze the juice from, with "out" | 44 |
| Squeeze out water, as of clothes | 32 |
| Squeeze by, with "out" | 32 |
| Squeeze album "__ Fan Tutti Frutti" | 45 |
| Squeeze (out), as water from a wet towel | 40 |
| Squeeze (out), as a narrow victory | 34 |
| Squeeze "___ Get Your Gun" | 36 |
| Squeeze "Another ___ in My Heart" | 43 |
| Squealed on, with "out" | 33 |
| Squeaks by, with "out" | 32 |
| Squash variety named for its shape | 34 |
| Square-dance caller's command | 33 |
| Square-bodied Desert Storm vehicle | 34 |
| Square's corner-to-corner line: Abbr. | 41 |
| Square that might have two sides? | 33 |
| Square that may have three sides? | 33 |
| Square peg in high school, perhaps | 34 |
| Square one of a child's game? | 33 |
| Square in the first column of bingo | 35 |
| Square in Google Calendar: Abbr. | 32 |
| Square in a public square, maybe | 32 |
| Square frequented by Holmes's circle | 40 |
| Square at the end of the fourth row in Battleship | 49 |
| Squad with red, white and blue uniforms | 39 |
| Squad that plays in the Coliseum | 32 |
| Squad for which LeBron James won a championship | 47 |
| Spyri's children's story | 32 |
| Spying against one's own country, say | 41 |
| Spy's reaction to an early retirement offer? | 48 |
| Spy's query at the start of a meeting | 41 |
| Spy's info acquisition, for short | 37 |
| Spy's briefing contents, briefly | 36 |
| Spy's acquisition, for short | 32 |
| Spy's "covert" activities | 39 |