| Botswana desert region | 22 |
| Bothersome engine noise | 23 |
| Bothers over trivial things | 27 |
| Bothers à la baby brother | 28 |
| Bother, with "at" | 27 |
| Bother the heck out of | 22 |
| Bother some space vehicles? | 27 |
| Bother over trivialities | 24 |
| Bother or trouble ending | 24 |
| Bother à la the media | 24 |
| Both, in the beginning | 22 |
| Both, at the beginning | 22 |
| Both ways, to an electrician | 28 |
| Both sides of an issue | 22 |
| Both of racing's Unsers | 27 |
| Both ends of a macrocosm? | 25 |
| Both Bushes, college-wise | 25 |
| Botches, with "up" | 28 |
| Botches (with "up") | 29 |
| Botch, with "up" | 26 |
| Botch the subtitles, maybe | 26 |
| Botch the boss's letter | 27 |
| Botany's ____ theory | 24 |
| Botany major's hurdles? | 27 |
| Botanists' concerns | 23 |
| Botanist's workplace | 24 |
| Botanist's specimens | 24 |
| Botanist's specialty | 24 |
| Botanist's runners | 22 |
| Botanist's interest | 23 |
| Botanist's expertise | 24 |
| Botanist's concern | 22 |
| Botanist's category | 23 |
| Botanist Gray: 1810–88 | 29 |
| Botanist Gray and others | 24 |
| Botanist Gray and namesakes | 27 |
| Botanical ring of color | 23 |
| Botanical part: Suffix | 22 |
| Botanical nutrient conductor | 28 |
| Botanical intersection | 22 |
| Botanical group of blossoms? | 28 |
| Botanical gardens display | 25 |
| Botanical gardens (Var.) | 24 |
| Botanical garden display | 24 |
| Botanical branch point | 22 |
| Botanical "pet" | 25 |
| Bostonians rarely say them | 26 |
| Bostonian's favorite | 24 |
| Boston-to-Weymouth dir. | 23 |
| Boston-to-The Cape dir. | 23 |
| Boston-to-Providence dir. | 25 |
| Boston-to-Portland dir. | 23 |
| Boston-to-Pittsburgh dir. | 25 |
| Boston-to-Nantucket dir. | 24 |
| Boston-to-D.C. speedster | 24 |
| Boston-based beer brand | 23 |
| Boston-area university | 22 |
| Boston, ___ of America | 22 |
| Boston, with "the" | 28 |
| Boston, or one of its hits | 26 |
| Boston, for O. W. Holmes | 24 |
| Boston, Chicago or Kansas | 25 |
| Boston's trademark food | 27 |
| Boston's time, at times | 27 |
| Boston's TD Garden, e.g. | 28 |
| Boston's state: Abbr. | 25 |
| Boston's red items | 22 |
| Boston's only #1 hit | 24 |
| Boston's Number Four | 24 |
| Boston ___ (orchestra) | 22 |
| Boston ___ (MIT, once) | 22 |
| Boston University player | 24 |
| Boston U.'s terrier | 23 |
| Boston timepiece setting | 24 |
| Boston team, informally | 23 |
| Boston team, for short | 22 |
| Boston team, familiarly | 23 |
| Boston Tea ___: Dec. 16, 1773 | 29 |
| Boston Tea Party V.I.P. | 23 |
| Boston Tea Party tea, e.g. | 26 |
| Boston Tea Party planner | 24 |
| Boston Tea Party issue | 22 |
| Boston Tea Party impetus | 24 |
| Boston Symphony maestro | 23 |
| Boston Symphony conductor | 25 |
| Boston skyscraper, familiarly | 29 |
| Boston skyscraper nickname | 26 |
| Boston seafood selection | 24 |
| Boston seafood offering | 23 |
| Boston retired his number 4 | 27 |
| Boston Red Sox after 1919? | 26 |
| Boston Pops instrument | 22 |
| Boston players, briefly | 23 |
| Boston player, informally | 25 |
| Boston player, for short | 24 |
| Boston player, briefly | 22 |
| Boston pier since the 1700s | 27 |
| Boston Patriots' org. | 25 |
| Boston patriot's plant | 26 |
| Boston or poison follower | 25 |