| 2 and 12, e.g., in dice | 23 |
| 2 Columbus Circle, some say | 27 |
| 2 winners at battle of bands | 28 |
| 2 _____ (double- teamed) | 24 |
| 2, 3, 5, 7, 11, 13, etc. | 24 |
| 2, 4, 6, 8, 10 ..., e.g. | 24 |
| 2, 4, 6, 8, and so forth | 24 |
| 2, at many a putt-putt | 22 |
| 2,000 pounds avoirdupois | 24 |
| 2,000-year-old French city | 26 |
| 2,240 pounds, in Britain | 24 |
| 2,502, to ancient Romans | 24 |
| 2,700-mile-long Asian river | 27 |
| 2,700-mile-long Russian river | 29 |
| 2,779-mile-long Russian river | 29 |
| 2,880-mile long country | 23 |
| 2-1 or 3-2, in baseball | 23 |
| 2-BR listings, perhaps | 22 |
| 2-in-1 hair care brand | 22 |
| 2-point Scrabble pieces | 23 |
| 2.0 GPA component, probably | 27 |
| 2.2 lbs., approximately | 23 |
| 2.5%/year interest, e.g. | 24 |
| 2/22/2022, aptly: Abbr. | 23 |
| 20 milligrams, perhaps | 22 |
| 20 short hundredweight | 22 |
| 20 years to life, e.g. | 22 |
| 20% of U.S. senators in 2014 | 28 |
| 20's beer barrel busters | 28 |
| 20's dispenser, for short | 29 |
| 20's dispensers, briefly | 28 |
| 20's gangster Bugs ___ | 26 |
| 20's heavyweight Tunney | 27 |
| 20's-30's cars | 22 |
| 20's-50's papal name | 28 |
| 20, in the Gettysburg Address | 29 |
| 20,320-foot Alaskan peak | 24 |
| 20-0 baseball score, say | 24 |
| 20-hour-week worker, e.g. | 25 |
| 20-ounce Starbucks order | 24 |
| 20-vol. reference work | 22 |
| 200 expensive milligrams | 24 |
| 200 in the Indianapolis 500 | 27 |
| 200 milligrams of opals | 23 |
| 200 milligrams, to a jeweler | 28 |
| 200 precious milligrams | 23 |
| 2000 #1 hit for Santana | 23 |
| 2000 American League MVP | 24 |
| 2000 B.C. and A.D., e.g. | 24 |
| 2000 Ben Affleck thriller | 25 |
| 2000 Ben Kingsley crime drama | 29 |
| 2000 Ben Kingsley film | 22 |
| 2000 Ben Stiller comedy | 23 |
| 2000 Best Picture nominee | 25 |
| 2000 Best Song Oscar winner | 27 |
| 2000 Britney Spears hit | 23 |
| 2000 Bruce Willis film | 22 |
| 2000 Cameron Crowe movie | 24 |
| 2000 Camp David visitor | 23 |
| 2000 custody-fight kid | 22 |
| 2000 De Niro/Stiller comedy | 27 |
| 2000 election debacle? | 22 |
| 2000 Flushes alternative | 24 |
| 2000 Green Party candidate | 26 |
| 2000 Home Run Derby winner | 26 |
| 2000 Hugh Jackman film | 22 |
| 2000 Hugh Jackman movie | 23 |
| 2000 Jackie Chan movie | 22 |
| 2000 Jennifer Lopez thriller | 28 |
| 2000 Kyocera acquisition | 24 |
| 2000 Liev Schreiber film | 24 |
| 2000 Martin Lawrence movie | 26 |
| 2000 memoir by Stephen King | 27 |
| 2000 N.B.A. championship star | 29 |
| 2000 N.L. home run champ | 24 |
| 2000 National League MVP Jeff | 29 |
| 2000 newsmaker Gonzalez | 23 |
| 2000 Olympic gymnast ___ Ray | 28 |
| 2000 Olympics greeting | 22 |
| 2000 Olympics platypus mascot | 29 |
| 2000 Oscar nominee Lee | 22 |
| 2000 Peter Gabriel album | 24 |
| 2000 polling place litter | 25 |
| 2000 presidential also-ran | 26 |
| 2000 presidential candidate | 27 |
| 2000 presidential hopeful | 25 |
| 2000 Richard Gere role | 22 |
| 2000 Richard Gere title role | 28 |
| 2000 Stanley Cup champions | 26 |
| 2000 Subway Series losers | 25 |
| 2000 Subway Series stadium | 26 |
| 2000 Summer Olympics city | 25 |
| 2000 Summer Olympics mascot | 27 |
| 2000 Super Bowl champs | 22 |
| 2000 Super Bowl player | 22 |
| 2000 Super Bowl winner | 22 |
| 2000 Supreme Court case | 23 |
| 2000 title role for Gere | 24 |
| 2000 title role for Julia | 25 |
| 2000 title role for Renée | 28 |