| Influential Harper's Weekly cartoonist | 42 |
| Its first leader was Lord Ismay, 1952-1957 | 42 |
| India's longest-serving prime minister | 42 |
| Its source was discovered by John H. Speke | 42 |
| It might be hard-pressed to get assistance | 42 |
| Its ruins are across the Tigris from Mosul | 42 |
| It puts a team in the World Series (Abbr.) | 42 |
| Inappropriate for the easily offended, say | 42 |
| Instant, in a phrase (with "in") | 42 |
| Isolationist in the Senate: 1925–45 | 42 |
| Instrument often made from grenadilla wood | 42 |
| Instrument in NATO's phonetic alphabet | 42 |
| It may be written "on" something | 42 |
| It forms part of the Poland-Germany border | 42 |
| Instrument for measuring distance traveled | 42 |
| Its first capital was Chillicothe, 1803-10 | 42 |
| It's sometimes deep-fried in the South | 42 |
| Ingredient in some "light" chips | 42 |
| It's enough to bring a tear to the eye | 42 |
| It may precede sex or surgery (Tribute #4) | 42 |
| It follows a dot in many on-line addresses | 42 |
| Its mouth was discovered by Columbus: 1498 | 42 |
| Item most frequently heated up for dinner? | 42 |
| It surrounds the puzzles' long answers | 42 |
| Implement for a confident crossword solver | 42 |
| It's held by someone who's packing | 42 |
| Item in a box with seven compartments, say | 42 |
| It often goes before a fall, it's said | 42 |
| It's usually taken by high school jrs. | 42 |
| Intimidates mentally, with "out" | 42 |
| In the U.S., it has more than 950 stations | 42 |
| Indentation at the bottom of a wine bottle | 42 |
| Increase in intensity, with "up" | 42 |
| It costs at least fifty bucks on Boardwalk | 42 |
| Important parts of Thanksgiving and Easter | 42 |
| Items in a personnel director's in-box | 42 |
| Interchangeable with, with "the" | 42 |
| If it's repeated, it's nothing new | 42 |
| Italian city with an annual music festival | 42 |
| It's heard in "Besame Mucho" | 42 |
| It swallowed Amittai's son: Jonah 1:17 | 42 |
| I Have ____: West Side Story song | 42 |
| Ibsen play with the most flowery language? | 42 |
| It can be military, commercial, or general | 42 |
| It's unpleasant when things end on one | 42 |
| It may be required when a mortgage matures | 42 |
| Indiana senator discusses monetary policy? | 42 |
| IM shorthand while running to the bathroom | 42 |
| It has a close "Kentucky" cousin | 42 |
| Investigation of one person after another? | 42 |
| It went coed 8/24/96, with "The" | 42 |
| Its workers aren't behind closed doors | 42 |
| Injured baseball players go on them: abbr. | 42 |
| It may be illegal to call while doing this | 42 |
| In a manner conforming to social standards | 42 |
| Ici ___ (here and there, to Thérèse) | 42 |
| It included the Eastern and Western fronts | 42 |
| If ____ Would Leave You : Camelot ballad | 42 |
| Intelligence explanation, perhaps (Part 2) | 42 |
| Indicator of success in life, to a palmist | 42 |
| Instant message between you and 3 friends? | 42 |
| Is tied up by "the Man in Black" | 42 |
| Injuries sustained at the O.K. Corral, say | 42 |
| Instruction heard at a zoo exercise class? | 42 |
| It's placed midway between the gutters | 42 |
| It may get going when the going gets tough | 42 |
| It's not a lot, but you can live on it | 42 |
| Improper way to write 59 in Roman numerals | 42 |
| It's just to the left of Baltic Avenue | 42 |
| Imaginative child's companion, perhaps | 42 |
| If any deity were to have a great tan, ___ | 42 |
| Its rededication is celebrated at Hanukkah | 42 |
| Infamous settler on Galveston Island, 1817 | 42 |
| Italy's _____ Islands, north of Sicily | 42 |
| It's probably better not to answer one | 42 |
| Italian author ("L'Esclusa") | 42 |
| INSURGENT'S PARKA IS GUNFIRE CASUALTY! | 42 |
| Italian site of an 1800 Napoleonic victory | 42 |
| In a ___, you can periodically catch a ___ | 42 |
| It's not long in going down a mountain | 42 |
| It may be pressed during a conference call | 42 |
| Its eastern end passes south of Youngstown | 42 |
| It's raised in some opening ceremonies | 42 |
| It may be standing at the end of a concert | 42 |
| It is used for what's already happened | 42 |
| Its brands include Frito-Lay and Tropicana | 42 |
| It's found near Home, often, for short | 42 |
| In myth she was changed into a nightingale | 42 |
| It was named Hamm in "Toy Story" | 42 |
| Its teeth were actually a chimpanzee's | 42 |
| Indoor fixtures in a famous Italian tower? | 42 |
| It's a reason to decline an invitation | 42 |
| Institution that commemorates malpractice? | 42 |
| It begins after one's last day at work | 42 |
| Ice skating area that's totally green? | 42 |
| Insect that's an agent to celebrities? | 42 |
| Important quality in products for toddlers | 42 |
| Its three strings are plucked with a bachi | 42 |
| It's gradually shrinking in the Arctic | 42 |
| It follows the octave in an Italian sonnet | 42 |