| Sacred scriptures of Islam | 26 |
| Sacred serpent, to Isis | 23 |
| Sacred symbols at Thebes | 24 |
| Sacred symbols on uraei | 23 |
| Sacred synagogue cabinets | 25 |
| Sacred volcano of Japan | 23 |
| Sacred wader of old Egypt | 25 |
| Sacred Zoroastrian writings | 27 |
| Sacred-texts.com index: Abbr. | 29 |
| Sacrifice attempt, perhaps | 26 |
| Sacrifice fly result, often | 27 |
| Sacrifice quality for speed | 27 |
| Sacrifice result, perhaps | 25 |
| Sacrifice site, in Siena | 24 |
| Sacrificial chess opening | 25 |
| Sacrificial spot, perhaps | 25 |
| Sacrificial stratagems | 22 |
| Sacro___ (anatomical region) | 28 |
| Sacrum or parietal, e.g. | 24 |
| Sacs that may get attacks | 25 |
| Sad horn sound, in memes | 24 |
| Sad letters for latecomers | 26 |
| Sad news item, for short | 24 |
| Sad notice in the paper | 23 |
| Sad notices, for short | 22 |
| Sad or wrought follower | 23 |
| Sad person's award? | 23 |
| Sad place for monks to live? | 28 |
| Sad Sack's girlfriend | 25 |
| Sad words from a speed cop | 26 |
| Sad, as a jilted lover | 22 |
| Sad, mad dad, in drama | 22 |
| Sad-happy, good-bad, etc. | 25 |
| Sad-sounding car company? | 25 |
| Sad-sounding musical interval | 29 |
| Sadat's domain: Abbr. | 25 |
| Sadat's land: Abbr. | 23 |
| Sadat's predecessor | 23 |
| SADD tries to prevent it | 24 |
| Saddam Hussein adviser Tariq | 28 |
| Saddam Hussein's group | 26 |
| Saddam Hussein's land | 25 |
| Saddam Hussein's title | 26 |
| Saddam Hussein, for one | 23 |
| Saddam Hussein, notably | 23 |
| Saddam used to rule it | 22 |
| Saddam's domain, once | 25 |
| Saddens, with "out" | 29 |
| Saddle __ (cowboy's woe) | 28 |
| Saddle ___ (cowboy's woe) | 29 |
| Saddlemaker's tool | 22 |
| Saddler's instrument | 24 |
| Saddler's materials | 23 |
| Saddlers' products | 22 |
| Sadducee's opponent | 23 |
| Sadie Hawkins Day creator | 25 |
| Sadie Hawkins Day originator | 28 |
| Sadie Hawkins Day racer | 23 |
| Sadie Hawkins Day suitors | 25 |
| Sadie Hawkins neighbor | 22 |
| Sadie of "Rain" | 25 |
| Sadist Amin with six wives | 26 |
| Sadly absent, as the departed | 29 |
| Sadly, to conductor Muti | 24 |
| Safari animal, informally | 25 |
| Safari beast, for short | 23 |
| Safari guide's other job? | 29 |
| Safari leader's title | 25 |
| Safari sight, sometimes | 23 |
| Safari sighting, for short | 26 |
| Safari transport, briefly | 25 |
| Safari truck, for short | 23 |
| Safari's assumed opening | 28 |
| Safari-inspired weekend wear | 28 |
| Safe and __ (out of danger) | 27 |
| Safe conversation topic | 23 |
| Safe from a skunk, say | 22 |
| Safe from a storm, as a plane | 29 |
| Safe from approaching danger | 28 |
| Safe investment choices | 23 |
| Safe investment rating | 22 |
| Safe investment, informally | 27 |
| Safe place for a cyclist | 24 |
| Safe place for cyclists | 23 |
| Safe place for lots of money | 28 |
| Safe place in the ring | 22 |
| Safe place, in Italian | 22 |
| Safe places to leave babies | 27 |
| Safe portfolio investments | 26 |
| Safe to ingest and digest | 25 |
| Safe Toys and Gifts Mo. | 23 |
| Safe, as an investment | 22 |
| Safe, as some mushrooms | 23 |
| Safe-deposit box document | 25 |
| Safe-deposit box item, maybe | 28 |
| Safeco Field ballplayer | 23 |
| Safecracker's omelet | 24 |
| Safecrackers' noise? | 24 |
| Safecrackers, slangily | 22 |
| Safely at first or second | 25 |