| One taking the law into one's own hands | 43 |
| One taking the lead?: Abbr. | 27 |
| One taking the Pepsi Challenge | 30 |
| One taking the plunge | 21 |
| One taking the stage? | 21 |
| One taking things badly? | 24 |
| One taking things in | 20 |
| One taking things wrong? | 24 |
| One taking to the slopes | 24 |
| One taking too many courses | 27 |
| One taking up charges | 21 |
| One talking | 11 |
| One talking impertinently | 25 |
| One talking in a forest, maybe | 30 |
| One talking nonsense | 20 |
| One tapped for a fraternity | 27 |
| One target of Rachel Carson's "Silent Spring" | 59 |
| One target of the MMR vaccine | 29 |
| One targeted by military police | 31 |
| One Tarzan portrayer | 20 |
| One taxed | 9 |
| One taxed in Apr. | 17 |
| One teaching econ or psych, e.g. | 32 |
| One teaching econ, e.g. | 23 |
| One teaching psych, e.g. | 24 |
| One team in gym class | 21 |
| One team in the N.B.A. All-Star Game, with "the" | 58 |
| One team represents it in the Chick-fil-A Bowl: Abbr. | 53 |
| One teaspoon, maybe | 19 |
| One teaspoon, perhaps | 21 |
| One teaspoonful or two caplets, maybe | 37 |
| One telephone button | 20 |
| One telling you where to get off, for short? | 44 |
| One ten-millionth of a joule | 28 |
| One tending a brush fire? | 25 |
| One tending to a sprain, perhaps | 32 |
| One tending to steer out of control? | 36 |
| One tense | 9 |
| One tenth of a gram (named after an Ancient Greek coin) | 55 |
| One tenth: prefix | 17 |
| One term Ontario Premier Bob | 28 |
| One terminus of the GW Bridge | 29 |
| One Thanksgiving trimming | 25 |
| One that "eats shoots and leaves" | 43 |
| One that attends | 16 |
| One that bets are on | 20 |
| One that brings in the bucks? | 29 |
| One that creates a current in the current | 41 |
| One that deals in: Suffix | 25 |
| One that didn't show? | 25 |
| One that dilates | 16 |
| One that does: Suffix | 21 |
| One that doesn't belong | 27 |
| One that eats from bowls | 24 |
| One that eats: Comb. form | 25 |
| One that flies off shelves? | 27 |
| One that frees | 14 |
| One that gets a leg up? | 23 |
| One that gets around? | 21 |
| One that gets depressed during recitals | 39 |
| One that gets hit on the head | 29 |
| One that gets into hot water | 28 |
| One that gets locked in a boat | 30 |
| One that gets punched out | 25 |
| One that gets tongue-tied? | 26 |
| One that gives you an eyeful? | 29 |
| One that goes "pop" in a children's song | 54 |
| One that goes before | 20 |
| One that goes to school regularly | 33 |
| One that got away | 17 |
| One that hangs out at home? | 27 |
| One that has a stable upbringing | 32 |
| One that heads up the staff | 27 |
| One that intertwines | 20 |
| One that is often taken out back and beaten | 43 |
| One that issues forth | 21 |
| One that keeps bumping into senators? | 37 |
| One that keeps track? | 21 |
| One that lessens | 16 |
| One that litters | 16 |
| One that lives in a single cell? | 32 |
| One that made the most errors? | 30 |
| One that makes one | 18 |
| One that may balk | 17 |
| One that may be pregnant | 24 |
| One that might be humble | 24 |
| One that might be taken outside and beaten? | 43 |
| One that might catch a double dribble? | 38 |
| One that might take a gander | 28 |
| One that most people would prefer to put off meeting? | 53 |
| One that performs best when tired? | 34 |
| One that picks up the kids? | 27 |
| One that reclines | 17 |
| One that rules | 14 |
| One that serves the queen | 25 |
| One that SETI hopes to hear from | 32 |
| One that sheds | 14 |
| One that shoots | 15 |
| One that shoots the breeze? | 27 |
| One that squeaks by? | 20 |