| Nickname for a 3-million-year-old humanoid fossil | 49 |
| Senate Foreign Relations Committee chair, 2003-07 | 49 |
| Mario's brother in Nintendo's Mario Bros. | 49 |
| Maria's husband, on "Sesame Street" | 49 |
| More than craves (with ''after'') | 49 |
| Neil Young "Can't Believe Your ___" | 49 |
| Yankee Sparky who wrote "The Bronx Zoo" | 49 |
| Polite "yes" or "no" follower | 49 |
| ''Big'' burger, at McDonald's | 49 |
| Cary's costar in "I'm No Angel" | 49 |
| W.C.'s "My Little Chickadee" costar | 49 |
| Raquel's "Myra Breckinridge" costar | 49 |
| "The Song of the Earth" composer Gustav | 49 |
| Family name of twin Olympic skiers Phil and Steve | 49 |
| Fête du Travail is celebrated on its first day | 49 |
| Proverbial starting point on the corporate ladder | 49 |
| Drink whose name is Tahitian for "good" | 49 |
| Build Captain Nemo's versatile sailing craft? | 49 |
| Its flag is made of green, yellow and red stripes | 49 |
| Country where Bambara is the main spoken language | 49 |
| African nation with a green, yellow, and red flag | 49 |
| "Scenes From a ___" (Woody Allen movie) | 49 |
| ''My Dinner with Andre'' director | 49 |
| "Au revoir, les enfants" director Louis | 49 |
| Much sought-after title object, in a 1930 mystery | 49 |
| "Baby ___" (Amy Poehler/Tina Fey movie) | 49 |
| "That's All Right, ___" (Elvis hit) | 49 |
| "___ Can't Buy You Love," 1979 song | 49 |
| Pop music's Cass Elliot and Michelle Phillips | 49 |
| "A Bar at the Folies-Bergère" artist | 49 |
| ''Luncheon on the Grass'' painter | 49 |
| "Luncheon on the Grass" painter Edouard | 49 |
| "Le Déjeuner sur l'herbe" artist | 49 |
| Bizarre Chris Kattan character on "SNL" | 49 |
| Its cover is round so it doesn't fall through | 49 |
| Layer of the earth between the crust and the core | 49 |
| "From ___ to Mozart" (1980 documentary) | 49 |
| French revolutionary who met his end in a bathtub | 49 |
| "My Little __": 1950s Gale Storm sitcom | 49 |
| ___ Trench (deepest point on Earth's surface) | 49 |
| One whose motto means "Always Faithful" | 49 |
| His #13 was retired in 2000 by the Miami Dolphins | 49 |
| Career passing yardage record holder before Favre | 49 |
| Two-time Oscar winner for Best Adapted Screenplay | 49 |
| Donald Trump's wife between Ivana and Melania | 49 |
| Actress Gibbs who played the Jeffersons' maid | 49 |
| TV actress once married to "The Donald" | 49 |
| "Invaders From ___" (1953 sci-fi movie) | 49 |
| Word with "media" or "exodus" | 49 |
| Word you hear before you flip over the chessboard | 49 |
| Fishburne thriller (with ''The'') | 49 |
| Damon of ''The Bourne Ultimatum'' | 49 |
| ''The Simpsons'' creator Groening | 49 |
| He was Will Hunting, Private Ryan, and Mr. Ripley | 49 |
| First spin-off from "All in the Family" | 49 |
| Island between La-nai and Molokai, alphabetically | 49 |
| "Men Shall Know Nothing of This" artist | 49 |
| "Your Body is a Wonderland" singer John | 49 |
| Degree Bill Gates and Warren Buffett never earned | 49 |
| ___ Center (home arena of the Washington Wizards) | 49 |
| Unrewarding career, as coined by Douglas Coupland | 49 |
| Position that an up-and-comer is unlikely to take | 49 |
| Jim of "ABC's Wide World of Sports" | 49 |
| Year Michelangelo began work on "David" | 49 |
| Year of Columbus's last trip to the New World | 49 |
| Some "General Hospital" roles, in brief | 49 |
| Justin Timberlake's "Cry ___ River" | 49 |
| ". . . give ___ torch!": D. H. Lawrence | 49 |
| ''Coming of Age in Samoa'' author | 49 |
| "He sure plays a --- pinball" (The Who) | 49 |
| Oldie with "all alone and feeling blue" | 49 |
| The Persians conquered them under Cyrus the Great | 49 |
| ". . . the ___ shall inherit the Earth" | 49 |
| Timon and Uncle Max, in "The Lion King" | 49 |
| Tom's "You've Got Mail" co-star | 49 |
| Tom's "Sleepless in Seattle" costar | 49 |
| Prefix with "phone" or "byte" | 49 |
| Prefix for "bytes" or "bucks" | 49 |
| Kevin Kline's "French Kiss" co-star | 49 |
| Exclamation popularized by “The Simpsons” | 49 |
| "I could take it or leave it," slangily | 49 |
| "___ Leben," Wagner's autobiography | 49 |
| Best Director Oscar winner five years after Kevin | 49 |
| First National League player to hit 500 home runs | 49 |
| What was "Raining" on The Weather Girls | 49 |
| The start of the four theme entries, collectively | 49 |
| Entire "Glengarry Glen Ross" cast, e.g. | 49 |
| Biblical "handwriting on the wall" word | 49 |
| "Amahl and the Night Visitors" composer | 49 |
| "The Saint of Bleecker Street" composer | 49 |
| Walter Winchell's "___ of the week" | 49 |
| Certain exchange, for short, with "the" | 49 |
| "Something's Gotta Give" songwriter | 49 |
| Circle passing through both the earth's poles | 49 |
| Academy Award of ___ (official name for an Oscar) | 49 |
| "Wordplay" crossword constructor Reagle | 49 |
| "The Bottle Let Me Down" singer Haggard | 49 |
| Wine whose name means "young blackbird" | 49 |
| She played Julia in "Julie & Julia" | 49 |
| Recipient of a record 16 acting Oscar nominations | 49 |