| 15th century prince who was the inspiration for Dracula | 55 |
| 15th century Italian friar-turned-artist | 40 |
| 15th century date | 17 |
| 15th century caravel | 20 |
| 15th C. pontiff | 15 |
| 15th C. caravel | 15 |
| 15th anniversary gift | 21 |
| 15th Amendment topic | 20 |
| 15:40 at Charles De Gaulle, e.g. | 32 |
| 1598 edict site | 15 |
| 1598 edict city | 15 |
| 1589-92 teaching venue for Galileo | 34 |
| 1588 loser | 10 |
| 157° 30' | 15 |
| 1571 battle site where Cervantes lost the use of his left hand | 62 |
| 157.5° | 14 |
| 157.5° to a mariner | 22 |
| 157.5° from N | 16 |
| 157.5 degrees, to a pilot | 25 |
| 157.5 degrees fron N | 20 |
| 157.5 degrees from S | 20 |
| 157.5 degrees from N | 20 |
| 157.5 degrees | 13 |
| 156, to Livy | 12 |
| 1558-1603 monarch: Abbr. | 24 |
| 1555, to Caesar | 15 |
| 1554, the old way | 17 |
| 1552, on a cornerstone | 22 |
| 1551, on monuments | 18 |
| 1551, in monuments | 18 |
| 1550, to Flavius | 16 |
| 1550, in old Rome | 17 |
| 1550 | 4 |
| 155-mm. gun | 11 |
| 155-mi. Asian strip that intersects the 38th parallel | 53 |
| 155, to some | 12 |
| 155, in Roman numerals | 22 |
| 155, in old Rome | 16 |
| 1545-63 council site | 20 |
| 1545 council site | 17 |
| 154, to Livy | 12 |
| 154 minutes of Whoopi Goldberg just mixing red and blue paint? | 62 |
| 1521 visitor to Guam | 20 |
| 1521 stop for Magellan | 22 |
| 152, to Cato | 12 |
| 152, in Roman numerals | 22 |
| 1519 Yucatán arrival | 23 |
| 1516 classic originally written in Latin | 40 |
| 1513 isthmus crosser | 20 |
| 1511, to Fabius | 15 |
| 1510, to some | 13 |
| 1510, in Rome | 13 |
| 151, to Claudius | 16 |
| 151, to Cato | 12 |
| 151, to Caesar | 14 |
| 151, on a monument | 18 |
| 151, in Roman numerals | 22 |
| 151, in old Rome | 16 |
| 151 to Big Julie | 16 |
| 151 on a monument | 17 |
| 151 in old Rome | 15 |
| 1507 masterpiece | 16 |
| 1506, in Roman numerals | 23 |
| 1504, to Caesar | 15 |
| 1502, to Caesar | 15 |
| 1502, on monuments | 18 |
| 1502, on a monument | 19 |
| 1501, to Nero | 13 |
| 1501, to Caesar | 15 |
| 1501, on a monument | 19 |
| 1501, in Roman numerals | 23 |
| 1501, in old Europe | 19 |
| 1501, in ancient Rome | 21 |
| 1501 in Roma | 12 |
| 1500s painter known for his "Lives" of Italian artists | 64 |
| 1500-mile river to the Caspian Sea | 34 |
| 1500-meter winner at the 1964 Olympics | 38 |
| 1500 | 4 |
| 150-miles-per-hour Amtrak train | 31 |
| 150% of due | 11 |
| 150 percent of due | 18 |
| 150 followers of Job? | 21 |
| 150 followers of Job | 20 |
| 15.4324 grains troy | 19 |
| 15.432 grains | 13 |
| 15-year-old, legally | 20 |
| 15-time Primetime Emmy nominee | 30 |
| 15-time NBA All-Star Kevin | 26 |
| 15-time N.B.A. All-Star who announced his retirement on Twitter | 63 |
| 15-percenters: Abbr. | 20 |
| 15-percenter: Abbr. | 19 |
| 15-percenter | 12 |
| 15-ml unit | 10 |
| 15-minute CDs | 13 |
| 15-ball cluster | 15 |
| 15-21-13-1-18-6 | 15 |
| 15-15 or 40-40 | 14 |
| 15-0 in baseball, e.g. | 22 |
| 15, for any row, column or diagonal of a 3x3 magic square | 57 |
| 15, 30, 45, ___ | 15 |