| 1988 Ryan/Quaid remake | 22 |
| 1988 Rob Lowe/Meg Tilly thriller | 32 |
| 1988 remake directed by the creators of Max Headroom | 52 |
| 1988 Rebecca De Mornay comedy | 29 |
| 1988 Radio Hall of Fame inductee, with "The" | 54 |
| 1988 Radio Hall of Fame inductee | 32 |
| 1988 Quaid/Ryan thriller | 24 |
| 1988 Quaid/Ryan movie | 21 |
| 1988 purchaser of Motown | 24 |
| 1988 presidential hopeful | 25 |
| 1988 presidential candidate | 27 |
| 1988 platinum-selling country album | 35 |
| 1988 Peter Allen musical | 24 |
| 1988 Oscar-winning song | 23 |
| 1988 Oscar nominee Edward James ___ | 35 |
| 1988 Olympics swimming sensation | 32 |
| 1988 Olympics superheavyweight gold medalist | 44 |
| 1988 Olympics sprinter, familiarly | 34 |
| 1988 Olympics site | 18 |
| 1988 Olympics setting | 21 |
| 1988 Olympics nickname | 22 |
| 1988 Olympics locale | 20 |
| 1988 Olympics host | 18 |
| 1988 Olympics city | 18 |
| 1988 Olympic track star, informally | 35 |
| 1988 Olympic track star nickname | 32 |
| 1988 Olympic sprinter, popularly | 32 |
| 1988 Olympic gold-medal swimmer Kristin | 39 |
| 1988 Olympic gold medalist Carolyn | 34 |
| 1988 Olympic Games city | 23 |
| 1988 noir remake | 16 |
| 1988 Nobelist in chemistry | 26 |
| 1988 Nobel Prize sharer | 23 |
| 1988 Nielsen movie | 18 |
| 1988 NFL MVP | 12 |
| 1988 National League Rookie of the Year Chris | 45 |
| 1988 N.L. Rookie of the Year Chris | 34 |
| 1988 N.F.L. M.V.P. | 18 |
| 1988 movie, 'Without --' | 32 |
| 1988 movie based on the novel "The Grizzly King" | 58 |
| 1988 Motown Records purchaser | 29 |
| 1988 Motown acquirer | 20 |
| 1988 Miss America winner Kaye Lani ___ Rafko | 44 |
| 1988 Midler/Tomlin farce | 24 |
| 1988 Michener epic | 18 |
| 1988 Michener book | 18 |
| 1988 Michelle Pfeiffer film | 27 |
| 1988 Michelle Pfeiffer comedy | 29 |
| 1988 Michael Keaton drama | 25 |
| 1988 Meryl Streep film | 22 |
| 1988 Meg Ryan thriller | 22 |
| 1988 Meg Ryan film | 18 |
| 1988 Masters winner | 19 |
| 1988 marathon gold medalist Rosa ___ | 36 |
| 1988 LL Cool J hit "Going Back to ___" | 48 |
| 1988 Kevin Costner movie | 24 |
| 1988 Kennedy Center Honors recipient | 36 |
| 1988 Jonathan Demme film | 24 |
| 1988 Johnny Unitas Golden Arm Award winner Rodney | 49 |
| 1988 John Sayles film, in Rome? | 31 |
| 1988 John Cusack film | 21 |
| 1988 John Cleese movie, with "A" | 42 |
| 1988 Joe Keenan novel (2,7) | 27 |
| 1988 Jean Claude Van Damme film, or where an L.A. gang docks their boats? | 73 |
| 1988 Japanese animated cyberpunk action movie | 45 |
| 1988 inductees into the Rock and Roll Hall of Fame | 50 |
| 1988 hit for the Beach Boys | 27 |
| 1988 hit for Pebbles | 20 |
| 1988 hit for Breathe | 20 |
| 1988 Heisman winner Barry | 25 |
| 1988 Heisman Trophy winner | 26 |
| 1988 Heisman Trophy runner-up Rodney | 36 |
| 1988 Hanks film with a fortune-telling machine | 46 |
| 1988 Grand Slam winner | 22 |
| 1988 Grammy winner for "Crying" | 41 |
| 1988 film with the line "I'm an excellent driver" | 63 |
| 1988 film that precipitated the Buchwald v. Paramount lawsuit | 61 |
| 1988 film set in a New England pie maker's shop | 51 |
| 1988 film remake starring Dennis Quaid | 38 |
| 1988 film noir remake | 21 |
| 1988 film farce fish | 20 |
| 1988 film costarring Robert De Niro and Charles Grodin | 54 |
| 1988 film about Charlie Parker | 30 |
| 1988 film about an optimistic broker? | 37 |
| 1988 film "Rent-___" | 30 |
| 1988 fantasy film | 17 |
| 1988 Errol Morris documentary about the murder of a police officer, with "The" | 88 |
| 1988 Edward James Olmos film | 28 |
| 1988 earthquake site | 20 |
| 1988 Dreyfuss-Julia comedy | 26 |
| 1988 Don DeLillo novel | 22 |
| 1988 Dick Francis thriller, with "The" | 48 |
| 1988 Dennis Quaid/Meg Ryan movie | 32 |
| 1988 Dennis Quaid thriller | 26 |
| 1988 Dennis Quaid remake | 24 |
| 1988 Dennis Quaid film | 22 |
| 1988 Danzig single | 18 |
| 1988 Cy Young winner Hershiser | 30 |
| 1988 Cusack film | 16 |
| 1988 country album | 18 |