| 2001 Cage role | 14 |
| 2001 British Open winner David | 30 |
| 2001 British Open champion David ___ | 36 |
| 2001 British Open champion David | 32 |
| 2001 British Open champion | 26 |
| 2001 boxing biopic | 18 |
| 2001 black-and-white film noir starring Billy Bob Thornton | 58 |
| 2001 biopic starring Will Smith | 31 |
| 2001 biopic directed by Michael Mann | 36 |
| 2001 biopic | 11 |
| 2001 biographical film | 22 |
| 2001 best seller about competitive Scrabble | 43 |
| 2001 Best New Artist Grammy winner | 34 |
| 2001 Best Community Site Webby winner | 37 |
| 2001 Ben Stiller film | 21 |
| 2001 Ben Affleck movie | 22 |
| 2001 bankruptcy filer | 21 |
| 2001 bankruptcy company | 23 |
| 2001 Audrey Tautou film | 23 |
| 2001 Asia album | 15 |
| 2001 Anjelica Huston miniseries, with "The" | 53 |
| 2001 and 2010, for ex. | 22 |
| 2001 and 2010 | 13 |
| 2001 album with the song "Love Don't Cost a Thing" | 64 |
| 2001 album with the #1 hit "Ain't It Funny" | 57 |
| 2001 album that debuted at #1 | 29 |
| 2001 album including the song "Love Don't Cost a Thing" | 69 |
| 2001 album featuring "Love Don't Cost a Thing" | 60 |
| 2001 A.L. MVP __ Suzuki | 23 |
| 2001 A.L. M.V.P and Rookie of the Year | 38 |
| 2001 "remake" of a 1936 novel | 39 |
| 2001 #1 hit for Jennifer Lopez | 30 |
| 2001 #1 album with the hit "Love Don't Cost a Thing" | 66 |
| 2001 to Augustus | 17 |
| 2001 in old Rome | 17 |
| 2001 name | 12 |
| 2001 computer name | 21 |
| 2001 computer | 16 |
| 2001 | 4 |
| 2000s, e.g.: Abbr. | 18 |
| 2000s wireless company | 22 |
| 2000s White House nickname | 26 |
| 2000s White House family | 24 |
| 2000s Vienna State Opera conductor | 34 |
| 2000s TV family | 15 |
| 2000s TV drama that ended in a church | 37 |
| 2000s TV drama set in the 1960s | 31 |
| 2000s teen drama whose opening theme was "California" | 63 |
| 2000s teen drama set in California | 34 |
| 2000s symbol of corporate misconduct | 36 |
| 2000s symbol of corporate financial misconduct | 46 |
| 2000s South African president Mbeki | 35 |
| 2000s sitcom starring a country singer | 38 |
| 2000s sitcom single mom | 23 |
| 2000s sitcom set in Texas | 25 |
| 2000s sitcom set in Houston | 27 |
| 2000s service site | 18 |
| 2000s Senate leader's turndown? | 35 |
| 2000s scandal subject | 21 |
| 2000s New Hampshire senator John | 32 |
| 2000s National Book Festival host | 33 |
| 2000s leadership nickname | 25 |
| 2000s Korean compact | 20 |
| 2000s Iraq war subject, briefly | 31 |
| 2000s Houston-based scandal subject | 35 |
| 2000s high school drama | 23 |
| 2000s HBO drama set in Utah | 27 |
| 2000s GM compacts | 17 |
| 2000s Giants manager Felipe | 27 |
| 2000s first lady Bush | 21 |
| 2000s events in North Korea, for short | 38 |
| 2000s drama set in Newport Beach | 32 |
| 2000s documentary whose first episode was "From Pole to Pole" | 71 |
| 2000s Chevy | 11 |
| 2000s CBS sitcom | 16 |
| 2000s caffeinated offshoot of 7 Up, based off an upside-down 7 Up logo | 70 |
| 2000s caffeinated offshoot of 7 Up | 34 |
| 2000s Bengals running back Dorsey | 33 |
| 2000–02 WNBA franchise | 29 |
| 2000-01 NBA MVP | 15 |
| 2000-01 Hart Memorial Trophy winner Joe | 39 |
| 2000, for one | 13 |
| 2000, e.g., in Spain | 20 |
| 2000, e.g. | 10 |
| 2000 Zellweger/Freeman flick | 28 |
| 2000 World Series venue | 23 |
| 2000 World Series team | 22 |
| 2000 World Series stadium | 25 |
| 2000 World Series site | 22 |
| 2000 World Series participant | 29 |
| 2000 World Series MVP Derek | 27 |
| 2000 World Series MVP | 21 |
| 2000 World Series manager | 25 |
| 2000 World Series M.V.P. | 24 |
| 2000 World Series losers | 24 |
| 2000 World Series locale | 24 |
| 2000 Woody Allen movie | 22 |
| 2000 Woody Allen film | 21 |
| 2000 was its year | 17 |
| 2000 Viacom purchase | 20 |