| Two-parent households | 21 |
| Two-part | 8 |
| Two-part answer | 15 |
| Two-part curves | 15 |
| Two-part David Bowie song from "Scary Monsters (and Super Creeps)" | 76 |
| Two-part drama by Shakespeare | 29 |
| Two-part drama that won two Best Play Tonys and a Best Miniseries Emmy | 70 |
| Two-part glove | 14 |
| Two-part glue | 13 |
| Two-part lake connected by the Strait of Tiquina | 48 |
| Two-part tile | 13 |
| Two-passenger carriage | 22 |
| Two-percent alternative | 23 |
| Two-performer act | 17 |
| Two-person | 10 |
| Two-person bands | 16 |
| Two-person basketball game | 26 |
| Two-person bike | 15 |
| Two-person board game | 21 |
| Two-person contest | 18 |
| Two-person conversation | 23 |
| Two-person country fair contest | 31 |
| Two-person cutting tool | 23 |
| Two-person David Mamet play | 27 |
| Two-person groups | 17 |
| Two-person log cutter | 21 |
| Two-person matchup on ice | 25 |
| Two-person pencil-and-paper game | 32 |
| Two-person plank | 16 |
| Two-person racing sled | 22 |
| Two-person ride | 15 |
| Two-person showdown | 19 |
| Two-person sled | 15 |
| Two-person starter home of note? | 32 |
| Two-person starter home? | 24 |
| Two-person table game | 21 |
| Two-person talks | 16 |
| Two-person teams | 16 |
| Two-person tool | 15 |
| Two-person trick-taking game | 28 |
| Two-piano piece | 15 |
| Two-piece | 9 |
| Two-piece bathing suit | 22 |
| Two-piece bedroom furniture | 27 |
| Two-piece chest | 15 |
| Two-piece fastening | 19 |
| Two-piece living room units | 27 |
| Two-piece outfit | 16 |
| Two-piece part | 14 |
| Two-piece piece | 15 |
| Two-piece pieces | 16 |
| Two-piece shooter, often | 24 |
| Two-piece suit | 14 |
| Two-piece suit that won't keep you warm | 43 |
| Two-piece suit's lack | 25 |
| Two-piece suit? | 15 |
| Two-piece suits | 15 |
| Two-piece suits? | 16 |
| Two-piece top | 13 |
| Two-piece wear | 14 |
| Two-piece? | 10 |
| Two-piecer top | 14 |
| Two-pipped cards | 16 |
| Two-player activity | 19 |
| Two-player basketball game | 26 |
| Two-player card game | 20 |
| Two-player hoops game | 21 |
| Two-player logic game with colored pegs | 39 |
| Two-player whist-like game | 26 |
| Two-ply molecular structure | 27 |
| Two-point football score | 24 |
| Two-point gridiron plays | 24 |
| Two-point plays in football | 27 |
| Two-point score | 15 |
| Two-point score in football | 27 |
| Two-point Scrabble tile | 23 |
| Two-point shot | 14 |
| Two-point throw in horseshoes | 29 |
| Two-pointer | 11 |
| Two-pointer in football | 23 |
| Two-pointer made with ease | 26 |
| Two-pointer of a sort | 21 |
| Two-pointer, the hard way | 25 |
| Two-pointers | 12 |
| Two-pointers in Scrabble | 24 |
| Two-pointers? | 13 |
| Two-position switch | 19 |
| Two-pronged | 11 |
| Two-pronged instrument | 22 |
| Two-pronged weapon | 18 |
| Two-Pulitzer biographer Robert | 30 |
| Two-purpose | 11 |
| Two-putts, often | 16 |
| Two-reel movie | 14 |
| Two-reeler about baseballer Darryl? | 35 |
| Two-reeler, e.g. | 16 |
| Two-rocker jam | 14 |
| Two-rod antenna | 15 |
| Two-run homer prerequisite | 26 |
| Two-run homer requirement | 25 |