| Two-handled Greek vase | 22 |
| Two-hanky film | 14 |
| Two-headed calf, for one | 24 |
| Two-headed drumsticks | 21 |
| Two-headed fastener | 19 |
| Two-headed lady exhibit, e.g. | 29 |
| Two-headed, three-armed President in the books referenced in this puzzle's theme | 84 |
| Two-holed feature | 17 |
| Two-horse bet | 13 |
| Two-horse wager | 15 |
| Two-hr. warning for Cinderella? | 31 |
| Two-hued sea predator | 21 |
| Two-hulled craft | 16 |
| Two-hulled vessel, for short | 28 |
| Two-humped camel | 16 |
| Two-in-one | 10 |
| Two-in-one creatures? | 21 |
| Two-inch nail | 13 |
| Two-inch putt, e.g. | 19 |
| Two-inch stripe wearer: Abbr. | 29 |
| Two-jawed device | 16 |
| Two-kind connector | 18 |
| Two-kind link | 13 |
| Two-l creatures | 15 |
| Two-L llama | 11 |
| Two-lane highway, maybe | 23 |
| Two-lane topper | 15 |
| Two-lane topper, often | 22 |
| Two-lanes-into-one highway sign | 31 |
| Two-layered candy | 17 |
| Two-layered gem | 15 |
| Two-legged | 10 |
| Two-legged creature | 19 |
| Two-legged livestock | 20 |
| Two-legged measurer | 19 |
| Two-legged measuring device | 27 |
| Two-legged measuring instruments | 32 |
| Two-legged meat source | 22 |
| Two-legged salamander | 21 |
| Two-legged sponge | 17 |
| Two-legged stand | 16 |
| Two-legged support | 18 |
| Two-legged wolf's look | 26 |
| Two-legged wolves' looks | 28 |
| Two-legged zebra | 16 |
| Two-letter combination | 22 |
| Two-letter combinations | 23 |
| Two-letter sequence | 19 |
| Two-line verse | 14 |
| Two-liter bottle contents | 25 |
| Two-liter bottle contents, sometimes | 36 |
| Two-man band? | 13 |
| Two-man competition | 19 |
| Two-man test of strength | 24 |
| Two-masted boats | 16 |
| Two-masted craft | 16 |
| Two-masted Dutch fishing vessel | 31 |
| Two-masted fore-and-after | 25 |
| Two-masted sailboat | 19 |
| Two-masted sailboats | 20 |
| Two-masted sailing ship | 23 |
| Two-masted sailing vessel | 25 |
| Two-masted sailing vessels | 26 |
| Two-masted ship | 15 |
| Two-masted ships | 16 |
| Two-masted vessel | 17 |
| Two-masted vessels | 18 |
| Two-master | 10 |
| Two-masters | 11 |
| Two-match link | 14 |
| Two-medium, as some rescues | 27 |
| Two-mile-high capital | 21 |
| Two-mile-high city | 18 |
| Two-mile-high menace | 20 |
| Two-minute warning giver | 24 |
| Two-month-old kid | 17 |
| Two-musician ensemble | 21 |
| Two-nation European peninsula | 29 |
| Two-nation peninsula | 20 |
| Two-ninths of MMCCLIX | 21 |
| Two-note announcement | 21 |
| Two-note instrument | 19 |
| Two-note keyboard effect | 24 |
| Two-of-a-kind vessel | 20 |
| Two-Oscar actor | 15 |
| Two-Oscar actor who loved crosswords | 36 |
| Two-Oscar actress | 17 |
| Two-Oscar Hilary | 16 |
| Two-Oscar knight | 16 |
| Two-Oscar winner for 1979 | 25 |
| Two-Oscar winner for 1984 | 25 |
| Two-Oscar winner Foster | 23 |
| Two-Oscar winner of '91 | 27 |
| Two-Oscar winner Sean | 21 |
| Two-out actions: Abbr. | 22 |
| Two-outs-in-a-single-AB stats | 29 |
| Two-page ad | 11 |
| Two-page ads | 12 |
| Two-palms-down signal | 21 |
| Two-paneled paintings | 21 |