| Twice from thrice | 17 |
| Twice halved | 12 |
| Twice less than thrice | 22 |
| Twice LI | 8 |
| Twice LII | 9 |
| Twice LIII | 10 |
| Twice LXXVI | 11 |
| Twice LXXVII | 12 |
| Twice nueve | 11 |
| Twice or more (with "once") | 37 |
| Twice or thrice | 15 |
| Twice Oscar-nominated actress for "Camille Claudel" and "The Story of Adele H." | 99 |
| Twice penta | 11 |
| Twice penta- | 12 |
| Twice plus once | 15 |
| Twice quadri- | 13 |
| Twice quatre | 12 |
| Twice quattuor | 14 |
| Twice quinze | 12 |
| Twice removed from thrice | 25 |
| Twice sei | 9 |
| Twice spun-off TV show set in Vegas | 35 |
| Twice tetra | 11 |
| Twice tetra- | 12 |
| Twice the radius | 16 |
| Twice the radius: Abbr. | 23 |
| Twice tre | 9 |
| Twice tres | 10 |
| Twice tri- | 10 |
| Twice triple | 12 |
| Twice uno | 9 |
| Twice vier | 10 |
| Twice VII | 9 |
| Twice VIII | 10 |
| Twice XXVI | 10 |
| Twice XXVIII | 12 |
| Twice XXXI | 10 |
| Twice zwei | 10 |
| Twice, "Notorious" band | 33 |
| Twice, a cheerleader's need | 31 |
| Twice, a deadly African fly | 27 |
| Twice, a deadly fly | 19 |
| Twice, a Gabor | 14 |
| Twice, a guitar effect used by Hendrix | 38 |
| Twice, a lollipop brand | 23 |
| Twice, a musical about marriage | 31 |
| Twice, a nasty fly | 18 |
| Twice, a New York Times puzzle | 30 |
| Twice, a noted Chinese dissident/artist | 39 |
| Twice, a Ramone | 15 |
| Twice, a Robin Williams sitcom catchphrase | 42 |
| Twice, a sweet onion variety | 28 |
| Twice, a Teletubby | 18 |
| Twice, a thiamine deficiency | 28 |
| Twice, a tot's stomach | 26 |
| Twice, an English rock band | 27 |
| Twice, an urban clothing brand | 30 |
| Twice, Chinese dissident artist Ai's given name | 51 |
| Twice, in music | 15 |
| Twice, Robert Kennedy's assassin | 36 |
| Twice, to Tiberius | 18 |
| Twice-a-month event | 19 |
| Twice-a-month tide | 18 |
| Twice-baked bread | 17 |
| Twice-baked breads | 18 |
| Twice-beaten Joe Louis challenger | 33 |
| Twice-broadcasted TV show | 25 |
| Twice-chewed food | 17 |
| Twice-convicted felon | 21 |
| Twice-daily commuting period | 28 |
| Twice-daily dozen (Abbr.) | 25 |
| Twice-funny chance? | 19 |
| Twice-heard sound | 17 |
| Twice-monthly oceanic event | 27 |
| Twice-monthly tide | 18 |
| Twice-overthrown leader of Haiti | 32 |
| Twice-secured | 13 |
| Twice-seen TV show | 18 |
| Twice-told | 10 |
| Twice-told TV tale | 18 |
| Twice-told ___ | 14 |
| Twice-yearly occurrence | 23 |
| Twice: Lat. | 11 |
| Twickenham toilet | 17 |
| Twickenham trucks | 17 |
| Twiddle one's thumbs | 24 |
| Twiddled digit | 14 |
| Twiddled one's thumbs | 25 |
| Twiddles one's thumbs | 25 |
| Twiddling one's thumbs | 26 |
| Twiddling thumbs | 16 |
| Twig | 4 |
| Twig broom | 10 |
| Twig brooms | 11 |
| Twig construction | 17 |
| Twig creation | 13 |
| Twig cut for grafting | 21 |
| Twig digs | 9 |
| Twig for basketry | 17 |
| Twig lookalikes | 15 |