| Second of the three Super Bowls in which Joe Montana was the MVP | 64 |
| Second of the sextet | 20 |
| Second of the plagues of Egypt | 30 |
| Second of the five stages of grief | 34 |
| Second of six? | 14 |
| Second of six for Henry VIII | 28 |
| Second of January | 17 |
| Second of four at college | 25 |
| Second of billions | 18 |
| Second of Ben Cartwright's sons | 35 |
| Second of April? | 16 |
| Second of all? | 14 |
| Second of all | 13 |
| Second of a word-processing pair | 32 |
| Second of a series | 18 |
| Second of a Roman's three names | 35 |
| Second of a restless pair | 25 |
| Second of a poetic trio | 23 |
| Second of a pair of letters swapped six times in this puzzle's theme entries | 80 |
| Second of a pair | 16 |
| Second of a musical tetralogy | 29 |
| Second of a Latin trio | 22 |
| Second of a Latin paradigm | 26 |
| Second of a Latin I trio | 24 |
| Second of a Latin 101 trio | 26 |
| Second of a historical trio | 27 |
| Second of a game trio | 21 |
| Second of a cereal trio | 23 |
| Second of a Caesarean trio | 26 |
| Second of 24 | 12 |
| Second of 12: Abbr. | 19 |
| Second occupation | 17 |
| Second O of OOO | 15 |
| Second O of O-O-O | 17 |
| Second nursery rhyme tumbler | 28 |
| Second notes of the scale | 25 |
| Second notes in diminished chords, in music | 43 |
| Second notes | 12 |
| Second notation at the bottom of a letter | 41 |
| Second New Testament book | 25 |
| Second nature | 13 |
| Second name? | 12 |
| Second name on the bill | 23 |
| Second name in inventors | 24 |
| Second name in inventions | 25 |
| Second name in cosmetics | 24 |
| Second name | 11 |
| Second NAACP president | 22 |
| Second Mrs. Chaplin | 19 |
| Second movement of Dvorák’s “New World” symphony | 63 |
| Second mother, of old | 21 |
| Second most populous Oklahoma city | 34 |
| Second most populous country | 28 |
| Second most populous continent: Abbr. | 37 |
| Second most populous city in Yemen | 34 |
| Second most populous city in Michigan | 37 |
| Second most populous Central American city | 42 |
| Second most populated country | 29 |
| Second most common Korean surname | 33 |
| Second mortgages, generally | 27 |
| Second mortgage, e.g. | 21 |
| Second mobster's query | 26 |
| Second mo. | 10 |
| Second miss in a hangman game, often | 36 |
| Second mate's kid? | 22 |
| Second match | 12 |
| Second Manassas victor | 22 |
| Second Manassas commander | 25 |
| Second man to walk on the moon | 30 |
| Second man on the moon | 22 |
| Second man off Apollo 11 | 24 |
| Second man | 10 |
| Second ltr. addition | 20 |
| Second ltr. addendum | 20 |
| Second ltr. addenda | 19 |
| Second lt.'s subordinate | 28 |
| Second Lt.'s Navy equivalent | 32 |
| Second lt.'s equivalent | 27 |
| Second look, on "Monday Night Football" | 49 |
| Second look | 11 |
| Second looies | 13 |
| Second looie | 12 |
| Second longest river in Poland | 30 |
| Second longest African river | 28 |
| Second lodging | 14 |
| Second line of verse | 20 |
| Second line of toast | 20 |
| Second line of the verse | 24 |
| Second line of the limerick | 27 |
| Second line of rhyme | 20 |
| Second line of quote | 20 |
| Second line of quip | 19 |
| Second line of pertinent rhyme | 30 |
| Second line of a nursery rhyme? | 31 |
| Second lightest element | 23 |
| Second Life hookup | 18 |
| Second Life fan, e.g. | 21 |
| Second life | 11 |
| Second lieutenants | 18 |
| Second lieutenant, slangily | 27 |