| Substantive substitutes | 23 |
| Substantives | 12 |
| Substitutable wd. | 17 |
| Substitute | 10 |
| Substitute (for) | 16 |
| Substitute a voice on a soundtrack | 34 |
| Substitute acquired by about half a million people a year: Abbr. | 64 |
| Substitute approved by the FDA in 1996 | 38 |
| Substitute at dinner | 20 |
| Substitute at the plate | 23 |
| Substitute at the stadium | 25 |
| Substitute bread spread | 23 |
| Substitute currency | 19 |
| Substitute decision? | 20 |
| Substitute dentist's activity? | 34 |
| Substitute doctors, in Britain | 30 |
| Substitute for | 14 |
| Substitute for a broken doorbell? | 33 |
| Substitute for a cart | 21 |
| Substitute for a forgotten lyric | 32 |
| Substitute for a jittery pilot? | 31 |
| Substitute for action | 21 |
| Substitute for an umbrella? | 27 |
| Substitute for boxers | 21 |
| Substitute for butt tissue, e.g.? | 33 |
| Substitute for dropped items | 28 |
| Substitute for forgotten words | 30 |
| Substitute for forgotten words in a song | 40 |
| Substitute for gum or Jove? | 27 |
| Substitute for some names | 25 |
| Substitute for some snack foods | 31 |
| Substitute for teeth in some whales | 35 |
| Substitute for the missing | 26 |
| Substitute for the unlisted | 27 |
| Substitute for the unnamed | 26 |
| Substitute for the unnamed, briefly | 35 |
| Substitute for unmentioned people | 33 |
| Substitute for unmentioned text | 31 |
| Substitute for, as a pitcher | 28 |
| Substitute guitarist? | 21 |
| Substitute handkerchief | 23 |
| Substitute in an emergency | 26 |
| Substitute in the kitchen | 25 |
| Substitute jurors | 17 |
| Substitute musician, often | 26 |
| Substitute new parts for old | 28 |
| Substitute performer | 20 |
| Substitute player | 17 |
| Substitute players | 18 |
| Substitute position | 19 |
| Substitute ruler | 16 |
| Substitute rulers | 17 |
| Substitute scepter-wielder | 26 |
| Substitute sovereigns | 21 |
| Substitute spread | 17 |
| Substitute word | 15 |
| Substitute's place | 22 |
| Substitute's preposition | 28 |
| Substitute, abbr. | 17 |
| Substitute, in a way | 20 |
| Substitute, in law | 18 |
| Substitute: Abbr. | 17 |
| Substitute; deputy | 18 |
| Substituted | 11 |
| Substituted (for) | 17 |
| Substituted for | 15 |
| Substitutes | 11 |
| Substitutes (for) | 17 |
| Substitutes for | 15 |
| Substitutes for forgotten words | 31 |
| Substitutes for gelatins | 24 |
| Substitutes for natural products | 32 |
| Substitutes' places | 23 |
| Substitutes: Abbr. | 18 |
| Substituting for (with ''of'') | 46 |
| Substituting for a Donald Trump wannabe? | 40 |
| Substituting for, in poetry | 27 |
| Substituting for, with "of" | 37 |
| Substitution in a list | 22 |
| Substitution word | 17 |
| Substratal water source | 23 |
| Subsurface finds | 16 |
| Subsurface hazard | 17 |
| Subsurface movement of water | 28 |
| Subsurface sources of water | 27 |
| Subsurface war vessel | 21 |
| Subsurface woodwork decoration | 30 |
| Subterfuge | 10 |
| Subterfuges | 11 |
| Subterfuges of sorts | 20 |
| Subterranean | 12 |
| Subterranean being of folklore | 30 |
| Subterranean burial site | 24 |
| Subterranean cemetery | 21 |
| Subterranean chamber | 20 |
| Subterranean complex | 20 |
| Subterranean dwarf | 18 |
| Subterranean hobbyist | 21 |
| Subterranean lines | 18 |
| Subterranean moisture level | 27 |