| Org. once led by Howard Dean | 28 |
| One who more than just talks | 28 |
| Oscar winner as Mr. Chipping | 28 |
| One of Dancer's partners | 28 |
| One with Type O blood, often | 28 |
| Object of Homer's desire | 28 |
| One of Morrison's group? | 28 |
| One with an entry-level job? | 28 |
| One who administers medicine | 28 |
| Overdo it with the grandkids | 28 |
| Olive ___ (uniform material) | 28 |
| Officer Friday's TV show | 28 |
| One shooting from the mouth? | 28 |
| One of 12 tiles in mah-jongg | 28 |
| Obstetrician's estimates | 28 |
| Operatic love scene, usually | 28 |
| One way to get to Washington | 28 |
| Old-school laundry detergent | 28 |
| Openings on football helmets | 28 |
| Openings in football helmets | 28 |
| Oregon-to-New York direction | 28 |
| One hanging around the house | 28 |
| Online shoppers might use it | 28 |
| Opposite of "endo" | 28 |
| One of four singing brothers | 28 |
| Old Olympic swimmer Gertrude | 28 |
| One may get laid on the farm | 28 |
| Ones with specialized esteem | 28 |
| Operation Exodus participant | 28 |
| One of Hollywood's Jacks | 28 |
| One way to reach new heights | 28 |
| One of the gridiron Mannings | 28 |
| Oscar-winning director Kazan | 28 |
| Old London Magazine essayist | 28 |
| Old Testament miracle worker | 28 |
| One of I. M. Pei's wings | 28 |
| Oceanographer's interest | 28 |
| Opera character with a dream | 28 |
| One-word Built to Spill song | 28 |
| Object of frequent sightings | 28 |
| Old bridge expert Culbertson | 28 |
| Online periodical, for short | 28 |
| On-line publication, briefly | 28 |
| Online publications, briefly | 28 |
| Online compilations, briefly | 28 |
| One way to deliver a message | 28 |
| One fleeing persecution, say | 28 |
| Oscar-winning actor Jannings | 28 |
| Olympic track legend Zatopek | 28 |
| One of the Brontës [1964] | 28 |
| One of Victoria's titles | 28 |
| Ostrich's kin down under | 28 |
| Ostrich's Aussie cousins | 28 |
| Orson Scott Card protagonist | 28 |
| Opposite of "ecto" | 28 |
| One of a famous set of twins | 28 |
| One of the Es in E.E.: abbr. | 28 |
| Only ape to circle the earth | 28 |
| Opposite of "free" | 28 |
| One-named Gaelic folk singer | 28 |
| One billion years to Hubble | 28 |
| Org. with an Office of Water | 28 |
| Org. whose seal has a flower | 28 |
| Org. that controls emissions | 28 |
| Org. doing atmospheric tests | 28 |
| Org. concerned with fracking | 28 |
| One of Vanuatu's islands | 28 |
| Omar of "Scream 2" | 28 |
| One way to remove marginalia | 28 |
| One way to get the lead out? | 28 |
| One way to get the word out? | 28 |
| One of a mythological ennead | 28 |
| One of Euterpe's sisters | 28 |
| One ten-millionth of a joule | 28 |
| Olympians Liddell and Heiden | 28 |
| One of the Menendez brothers | 28 |
| Oscar-winning role for Julia | 28 |
| Object of March celebrations | 28 |
| One of the winemaking Gallos | 28 |
| One way to get to first base | 28 |
| Originator of cutout dresses | 28 |
| Optical illusion illustrator | 28 |
| Odd, as a range of knowledge | 28 |
| One of a Mississippi quartet | 28 |
| Old brand along the turnpike | 28 |
| Old self-realization program | 28 |
| Open-shelved furniture piece | 28 |
| One of the film-making Coens | 28 |
| Old operating room substance | 28 |
| Old operating-room substance | 28 |
| On-line option for investors | 28 |
| Otherworldly ones, for short | 28 |
| One may get pins and needles | 28 |
| One of Zsa Zsa's sisters | 28 |
| One of Jolie's daughters | 28 |
| One group of numbers to pick | 28 |
| One of Bo-peep's charges | 28 |
| One catching a ram's eye | 28 |
| One with a complete sentence | 28 |
| One in a head office (abbr.) | 28 |