| Creator of Shmoos | 17 |
| Creator of Silas and Eppie | 26 |
| Creator of Skimbleshanks and Rumpelteazer | 41 |
| Creator of Sky Masterson | 24 |
| Creator of Skywalker and Solo | 29 |
| Creator of small cubes | 22 |
| Creator of some banks | 21 |
| Creator of some illusions | 25 |
| Creator of strange worlds | 25 |
| Creator of Stupefyin' Jones | 31 |
| Creator of sublime lines | 24 |
| Creator of Sula and Sethe | 25 |
| Creator of Tattered Tom | 23 |
| Creator of Tess | 15 |
| Creator of the Ragged Dick series | 39 |
| Creator of the ''Nautilus'' | 43 |
| Creator of the "Goosebumps" books | 43 |
| Creator of the "Microsoft sound" played when Windows 95 starts | 72 |
| Creator of the (current) world's fastest supercomputer | 58 |
| Creator of the annual Overlooked Film Festival | 46 |
| Creator of the back pages of some nonfiction books | 50 |
| Creator of the Bennet family | 28 |
| Creator of the Betamax tape format | 34 |
| Creator of the bronze "En Songe" | 42 |
| Creator of the Buddenbrooks | 27 |
| Creator of the character Bip | 28 |
| Creator of the character Mr. Brain | 34 |
| Creator of the characters M and Q | 33 |
| Creator of the chess champion Deep Blue | 39 |
| Creator of the Codex Leicester | 30 |
| Creator of the Corleones | 24 |
| Creator of the count of Monte Cristo | 36 |
| Creator of the crooner Johnny Fontane | 37 |
| Creator of the currency system consisting of galleons, sickles and knuts | 72 |
| Creator of the Democratic donkey | 32 |
| Creator of the Democrats' donkey | 36 |
| Creator of the detective C. Auguste Dupin | 41 |
| Creator of the detective Hercule | 32 |
| Creator of the Eloi | 19 |
| Creator of the Eloi and the Morlocks | 36 |
| Creator of the film characters Harry and Sally | 46 |
| Creator of the first animated cartoon | 37 |
| Creator of the first crossword | 30 |
| Creator of the first designer perfume | 37 |
| Creator of the G.O.P. elephant | 30 |
| Creator of the game Missile Command | 35 |
| Creator of the Grinch | 21 |
| Creator of the heroine Catherine Earnshaw | 41 |
| Creator of the Hundred Acre Wood | 32 |
| Creator of the Imagine Peace Tower | 34 |
| Creator of the Joads | 20 |
| Creator of the Keystone Kops | 28 |
| Creator of the Koran | 20 |
| Creator of the label Obscure Records | 36 |
| Creator of the leitmotif | 24 |
| Creator of the Lorax | 20 |
| Creator of the Lost Boys | 24 |
| Creator of the March family | 27 |
| Creator of the March sisters | 28 |
| Creator of the Marches | 22 |
| Creator of the Marches in "Little Women" | 50 |
| Creator of the Mayfair Witches | 30 |
| Creator of the McDonald's empire | 36 |
| Creator of the Moffats | 22 |
| Creator of the Morlocks | 23 |
| Creator of the New Yorker's typeface ___ Irvin | 50 |
| Creator of the Once-ler | 23 |
| Creator of the Owl and the Pussy-cat | 36 |
| Creator of the Oz books | 23 |
| Creator of the pigs Old Major and Napoleon | 42 |
| Creator of the Poor Soul | 24 |
| Creator of the QB position | 26 |
| Creator of the Ragged Dick books | 32 |
| Creator of the Red Cross Knight | 31 |
| Creator of the religion Bokononism | 34 |
| Creator of the republican elephant | 34 |
| Creator of the robots Primus and Helena | 39 |
| Creator of the Schmoos | 22 |
| Creator of the SEC | 18 |
| Creator of the secretary Della | 30 |
| Creator of the Shmoos | 21 |
| Creator of the Sneetches | 24 |
| Creator of the Snopes family | 28 |
| Creator of the solid-body electric guitar, a model of which still bears his name | 80 |
| Creator of the stuff of legends? | 32 |
| Creator of the Tammany Hall tiger | 33 |
| Creator of the Tammany tiger | 28 |
| Creator of the Three Laws of Robotics | 37 |
| Creator of the Three Musketeers | 31 |
| Creator of the Ushers | 21 |
| Creator of the Winged Monkeys | 29 |
| Creator of the Zax | 18 |
| Creator of Thidwick | 19 |
| Creator of Thidwick the Big-Hearted Moose | 41 |
| Creator of Thor | 15 |
| Creator of Threepio | 19 |
| Creator of Tigger and Roo | 25 |
| Creator of Tobacco Rhoda | 24 |
| Creator of Tommy and Tuppence | 29 |
| Creator of Topsy | 16 |