| Specialty for some thoroughbreds | 32 |
| Specialty in history as well as medicine? | 41 |
| Specialty of a Columbia school established in 1912 | 50 |
| Specialty of a couples therapist? | 33 |
| Specialty of a Library of Congress | 34 |
| Specialty of an M.D. who deals with head cases? | 47 |
| Specialty of certain "deliverymen" | 44 |
| Specialty of Charlie Parker | 27 |
| Specialty of Dionysus | 21 |
| Specialty of Edmond Hoyle | 25 |
| Specialty of Edward Scissorhands | 32 |
| Specialty of George Bancroft | 28 |
| Specialty of Keats | 18 |
| Specialty of Mantle and Maris | 29 |
| Specialty of Pythagoras | 23 |
| Specialty of quarter horses | 27 |
| Specialty of Robert McG. Thomas Jr. | 35 |
| Specialty of Russian painter Aivazovsky | 39 |
| Specialty of some artists | 25 |
| Specialty of some attorneys | 27 |
| Specialty of some bakers | 24 |
| Specialty of some doctors | 25 |
| Specialty of some MDs | 21 |
| Specialty of some sharks | 24 |
| Specialty of some tennis pros | 29 |
| Specialty of the funny Avon lady? | 33 |
| Specialty of Vanilla Ice | 24 |
| Specialty on an Innsbruck menu | 30 |
| Specialty oven | 14 |
| Specialty retailer since 1969 | 29 |
| Specialty retailer's focus | 30 |
| Specialty retailers' domains | 32 |
| Specialty sandwich from Domino's? | 37 |
| Specialty shoe width | 20 |
| Specialty shop | 14 |
| Specialty side dish for Norbit? | 31 |
| Specialty that involves the brain and spinal cord | 49 |
| Specialty, informally | 21 |
| Specialty, slangily | 19 |
| Specialty, so to speak | 22 |
| Specialty-food store | 20 |
| Speciate | 8 |
| Specie | 6 |
| Species | 7 |
| Species divisions | 17 |
| Species of buttercup | 20 |
| Species of deer | 15 |
| Species of falcon also called an American kestrel | 49 |
| Species of fir | 14 |
| Species of hickory | 18 |
| Species of lily | 15 |
| Species of Mexican yuccas | 25 |
| Species of narcissus | 20 |
| Species of ruminants | 20 |
| Species of Tolkien's Arwen Evenstar | 39 |
| Species of wheat | 16 |
| Species popular on YouTube | 26 |
| Species that serves as an early warning system | 46 |
| Species-crossing | 16 |
| Specific | 8 |
| Specific amount | 15 |
| Specific area | 13 |
| Specific area coverage | 22 |
| Specific duties | 15 |
| Specific gravity | 16 |
| Specific Happy Hour request | 27 |
| Specific heat: Abbr. | 20 |
| Specific hymnal | 15 |
| Specific item in a sleepwear collection? | 40 |
| Specific location | 17 |
| Specific longing | 16 |
| Specific market type | 20 |
| Specific printings | 18 |
| Specific quantity | 17 |
| Specific set of points, in math | 31 |
| Specific span of history | 24 |
| Specific talent | 15 |
| Specific time | 13 |
| Specific times in history | 25 |
| Specific vocabulary | 19 |
| Specific-gravity scale | 22 |
| Specifically | 12 |
| Specifically appointed group | 28 |
| Specifically as one likes | 25 |
| Specification | 13 |
| Specification at Thom McAn | 26 |
| Specification in a burger order, maybe [270 degrees] | 52 |
| Specification in a salad order | 30 |
| Specification in the ketchup aisle | 34 |
| Specification lead-in | 21 |
| Specification to a butcher | 26 |
| Specification to a butcher, perhaps | 35 |
| Specification with a steak order | 32 |
| Specification, colloquially | 27 |
| Specification, for short | 24 |
| Specification, so to speak | 26 |
| Specification: Abbr. | 20 |
| Specifications marked on 10-hole harmonicas | 43 |
| Specifications, slangily | 24 |
| Specifics | 9 |