| Differential-gear locale | 24 |
| Differin target, slangily | 25 |
| Difficult to a Cockney | 23 |
| Difficult and distasteful | 25 |
| Difficult and loathsome | 23 |
| Difficult and unpleasant | 24 |
| Difficult articulations | 23 |
| Difficult billiards shot | 24 |
| Difficult circumstances | 23 |
| Difficult computer of film | 26 |
| Difficult jump-rope game | 24 |
| Difficult kind of performance | 29 |
| Difficult one to deal with | 26 |
| Difficult pills to swallow | 26 |
| Difficult place to be in | 24 |
| Difficult place to walk | 23 |
| Difficult political situation | 29 |
| Difficult responsibility | 24 |
| Difficult road layouts | 22 |
| Difficult shoes to walk in | 26 |
| Difficult skating jump | 22 |
| Difficult things to make meet | 29 |
| Difficult time for Sosa | 23 |
| Difficult to carry, in a way | 28 |
| Difficult to change or break | 28 |
| Difficult to deal with | 22 |
| Difficult to detect, perhaps | 28 |
| Difficult to disentangle | 24 |
| Difficult to eradicate | 22 |
| Difficult to hold on to | 23 |
| Difficult to penetrate | 22 |
| Difficult to read, in a way | 27 |
| Difficult to reconcile | 22 |
| Difficult to straighten out | 27 |
| Difficult to understand | 23 |
| Difficult turn on the slopes | 28 |
| Difficult, as a situation | 25 |
| Difficult, to a cockney | 23 |
| Difficult-to-convince person | 28 |
| Difficult-to-pass driver | 24 |
| Difficult-to-predict outcome | 28 |
| Difficulties to be worked out | 29 |
| Difficulties with peroxide? | 27 |
| Difficulty with picking up | 26 |
| Difficulty with Z's? | 24 |
| Difficulty's opposite | 25 |
| Difficulty, so to speak | 23 |
| Difficulty, to the Bard | 23 |
| Diffused through a membrane | 27 |
| Diffusing by absorption | 23 |
| Diffusion through a membrane | 28 |
| Dig (up), as information | 24 |
| Dig discovery, perhaps | 22 |
| Dig in one's heels | 22 |
| Dig one's claws into | 24 |
| Dig up a treasure chest? | 24 |
| Dig up data for a thesis | 24 |
| Dig with the snout (Var.) | 25 |
| Dig, as for information | 23 |
| Dig, with "on" | 24 |
| Digest magazine founder Eric | 28 |
| Digestion and circulation | 25 |
| Digestion-aiding liquids | 24 |
| Digestive aid, to chemists | 26 |
| Digestive tract condition | 25 |
| Digestive tract malady | 22 |
| Digestive-system malady | 23 |
| Digger ___ of radio and TV | 26 |
| Digger's pottery find | 25 |
| Diggers for anthracite | 22 |
| Diggers or serving trays | 24 |
| Diggers' discoveries | 24 |
| Diggs of 'Chicago' | 26 |
| Diggs of "Chicago" | 28 |
| Diggs of "Rent" | 25 |
| Digit by the decimal point | 26 |
| Digit I, to scientists | 22 |
| Digit in military lingo | 23 |
| Digit sometimes stubbed | 23 |
| Digit that may be big? | 22 |
| Digit with a ring, maybe | 24 |
| Digital "V," maybe | 28 |
| Digital banking transaction | 27 |
| Digital book file extension | 27 |
| Digital business portmanteau | 28 |
| Digital camera battery, often | 29 |
| Digital camera inserts | 22 |
| Digital camera product | 22 |
| Digital camera setting | 22 |
| Digital camera type: Abbr. | 26 |
| Digital circuit acronym | 23 |
| Digital clock setting choice | 28 |
| Digital clock settings | 22 |
| Digital communication?: Abbr. | 29 |
| Digital computer of yore | 24 |
| Digital correspondence | 22 |
| Digital data transmitter | 24 |
| Digital device for piggies | 26 |
| Digital display, initially | 26 |
| Digital displays, for short | 27 |